I will discuss the problem of noise and fluctuations in cellular genetic and biochemical networks. In particular, I will describe three recently studied phenomena:
- Fluctuations in the number of molecules in the cell can lead to non-genetic individuality. Cells can regulate such fluctuations, as is observed, for instance, for chemotaxis network in E. coli.
- Some cellular networks show remarkable resistance to molecular noise. This seems to be the case for circadian clocks in cyanobacteria.
- Cells can also use phenotypic stochastic switching in order to survive in a fluctuating environment. This is the case of persistence in bacteria.
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Undergraduate Program for Bioinformatics and Systems Biology, |
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Graduate School of Information Science and Technology |
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Date： |
Oct 14 (Thu) |
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Time： |
2:00 - 3:30 pm |
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Place： |
Room 150, Faculty of Science, old bldg 1. |
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Host： |
Shinya Kuroda (ext 24697) |
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| Note that this seminar accompanies another seminar (I) by Prof. William F. Loomis
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