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CREST Symposium

The 1st International Symposium for Trans-Omics

Location:Koshiba Hall - Hongo Campus, the University of Tokyo (map)
Date: 21−22 Nov. 2017, JST
Registration Fee: free
Registration Form:the registration was closed
Abstract:The life system is a "trans-omic" network, consisting of interactions between numerous molecules across multi-omic layers, such as genome, transcriptome, proteome, and metabolome. Lifestyle diseases can be regarded as complex multifactorial diseases caused by breakdowns in a trans-omic network rather than breakdown of a single molecule. In spite of recent advances in measurement and analysis methods for single-omic layers, trans-omic analyses integrating multi-omic data have still been in a state of the art and under development. Here we hold this symposium to shed light on strategies and obstacles in integrating multiple omic layers to establish trans-omic approaches, and to have a discussion with cutting edge researchers in omics research fields. Furthermore, we propose "human whole body transomics", integrating trans-omic analyses for human whole organs, as an international milestone for rapid expansion of trans-omic approaches.

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Program
Day 1, 21st November
Opening remarks
13:00–13:10Tadashi Yamamoto - Research Supervisor, CREST
Session I
13:10–13:50Nathan E. Lewis - UCSD, USA
A multi-omics elucidation of the systemic regulation of metabolism through post-translational modifications
13:50–14:20Fumio Matsuda - Osaka Univ., Japan
Trans-omic analysis of the central metabolism of Saccharomyces cerevisiae by integration of metabolite concentration, metabolic flux, and enzyme abundance data
Session II
14:40–15:10Katsuyuki Yugi - RIKEN, Japan
Trans-omic analysis reveals fed and fasting insulin signal across phosphoproteome, transcriptome, and metabolome
15:10–15:40Mariko Okada - Osaka Univ., Japan
Trans-Omics analysis of NF-κB regulation
15:40–16:10Tatsuhiko Tsunoda - Tokyo Medical & Dental Univ., Japan
Trans-omic analysis drives precision medicine
Session III
16:30–17:00Takeshi Bamba - Kyushu Univ., Japan
Development of next generation metabolome analysis technologies for trans-omics
17:00–17:30Tomoyoshi Soga - Keio Univ., Japan
Multi-omics reveals MYC as a master regulator of colorectal cancer metabolism
Keynote
17:30–18:20Jens Nielsen - Chalmers Univ. of Technology, Sweden
Quantifying Global Rewiring of Metabolism in Cancer through Genome Scale Modeling
Day 2, 22nd November
Session IV
9:00–9:30Yibo Wu - RIKEN, Japan
Systems proteomics of liver mitochondria activity
9:30–10:00Hiroyuki Kubota - Kyushu Univ., Japan
Trans-omic analysis of the acute insulin action in the liver -Toward in vivo trans-omic analysis
10:00–10:30Takashi Ito - Kyushu Univ., Japan
Epigenome sequencing methods for comprehensive analysis of in vivo protein-DNA interactions and DNA methylation
Session V
10:50–11:30Sarah-Maria Fendt - VIB, Belgium
Nutrient metabolism – A driver of cancer
11:30–12:00Yutaka Suzuki - Univ. of Tokyo, Japan
Multi-omics analysis of cancer cells
Special lecture
13:30–14:00Craig Mak - Cell Systems, Editor
Perspectives on Publishing with Cell Systems
Keynote
14:00–14:50David E. James - Univ. of Sydney, Australia
Metabolic Cybernetics
Session VI
15:10–15:40Kei-ichi Nakayama - Kyushu Univ., Japan
Next-generation proteomics unveils a global landscape of cancer metabolism
15:40–16:10Shinya Kuroda - Univ. of Tokyo, Japan
Trans-omic analysis of the liver of lean and obese mice during an oral glucose administration
Closing remarks
16:10–16:20Shinya Kuroda - Univ. of Tokyo, Japan



Contact information
Department of Biological Sciences, Graduate School of Science, University of Tokyo
7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Shinya Kuroda
Tel: +81 3-5841-4699
Mail: hatano_AT_bs.s.u-tokyo.ac.jp (Personal: Hatano)
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