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(Akr1d1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 72 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 3920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301517" kegg_name "rno:301517" kegg_reaction0 "rn:R04807" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 27, subfamily a, polypeptide 1
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(Amacr, Da1-8, Marc1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 74 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 773.05 y 4561.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:252898" kegg_name "rno:252898" kegg_reaction0 "rn:R08735" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acyl-CoA oxidase 2, branched chain
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(Hsd17b4, MPF-2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 77 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 771.05 y 4901.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25541" kegg_name "rno:25541" kegg_reaction0 "rn:R03719" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "sterol carrier protein 2
(Scp2, NSLIPTR, SCPx)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 78 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 920.0 y 4900.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25541" kegg_name "rno:25541" kegg_reaction0 "rn:R04811" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "sterol carrier protein 2
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(Slc27a5, BAL, rBAL-1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 80 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 4030.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301517" kegg_name "rno:301517" kegg_reaction0 "rn:R08759" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 27, subfamily a, polypeptide 1
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(Slc27a5, BAL, rBAL-1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 84 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 650.0 y 4910.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29725" kegg_name "rno:29725" kegg_reaction0 "rn:R03718" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
(Baat, kan-1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 85 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5860.0 y 1920.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29725" kegg_name "rno:29725" kegg_reaction0 "rn:R03720" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
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(Slc27a5, BAL, rBAL-1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 88 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 920.05 y 3920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301517" kegg_name "rno:301517" kegg_reaction0 "rn:R04806" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 27, subfamily a, polypeptide 1
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(Amacr, Da1-8, Marc1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 92 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 920.0 y 4560.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:252898" kegg_name "rno:252898" kegg_reaction0 "rn:R08740" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acyl-CoA oxidase 2, branched chain
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(Hsd17b4, MPF-2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 94 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 776.05 y 4250.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:79111" kegg_name "rno:79111" kegg_reaction0 "rn:R08733" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "solute carrier family 27 (fatty acid transporter), member 5
(Slc27a5, BAL, rBAL-1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 95 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 750.05 y 3740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192242" kegg_name "rno:192242" kegg_reaction0 "rn:R04823" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
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(DEFINITION rCG53598-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 133 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3880.05 y 3500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24401+rno:25721" kegg_name "rno:24401 rno:25721" kegg_reaction0 "rn:R00355" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase etc.
(Got1, Aspat, Gaspat etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 134 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4290.05 y 3620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:289276+rno:684425" kegg_name "rno:289276 rno:684425" kegg_reaction0 "rn:R01135" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenylosuccinate synthase etc.
(Adss, Adss2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 135 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4290.05 y 3840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315150" kegg_name "rno:315150" kegg_reaction0 "rn:R01083" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenylosuccinate lyase
(Adsl, null)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 136 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3990.05 y 2940.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24792+rno:83784" kegg_name "rno:24792 rno:83784" kegg_reaction0 "rn:R00369" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "alanine-glyoxylate aminotransferase etc.
(Agxt, Spat etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 137 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3990.05 y 2900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:307759+rno:81670" kegg_name "rno:307759 rno:81670" kegg_reaction0 "rn:R00258" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glutamic pyruvate transaminase (alanine aminotransferase etc.
(Gpt2, ALT2, Cc2-5 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 138 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4330.05 y 2460.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24240" kegg_name "rno:24240" kegg_reaction0 "rn:R01397" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
(Cad)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 139 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5430.05 y 4000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24399" kegg_name "rno:24399" kegg_reaction0 "rn:R00243" kegg_reaction1 "rn:R00248" kegg_reaction_type0 "reversible" kegg_reaction_type1 "reversible" kegg_type "gene" ] label "glutamate dehydrogenase 1
(Glud1, Ac2-281, Gdh1, Glud, Gludeha, MRG-2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 140 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6110.05 y 3900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192268+rno:24398" kegg_name "rno:192268 rno:24398" kegg_reaction0 "rn:R00256" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glutaminase 2 (liver, mitochondrial etc.
(Gls2, Ga etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 141 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4020.05 y 4100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00940" kegg_name "cpd:C00940" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 142 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4020.05 y 4060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288174" kegg_name "rno:288174" kegg_reaction0 "rn:R00269" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "nitrilase family, member 2
(Nit2, RGD1310494)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 143 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3120.05 y 2600.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:297417+rno:360518" kegg_name "rno:297417 rno:360518" kegg_reaction0 "rn:R00768" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glutamine fructose-6-phosphate transaminase etc.
(Gfpt1, GFA, GFAT, GFAT1, GFAT1m, Gfpt etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 144 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4460.05 y 720.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:117544" kegg_name "rno:117544" kegg_reaction0 "rn:R01072" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosyl pyrophosphate amidotransferase
(Ppat, Atase)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 145 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.0 y 1790.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114089+rno:317576+rno:362590+rno:84018+rno:85238" kegg_name "rno:114089 rno:317576 rno:362590 rno:84018 rno:85238" kegg_reaction0 "rn:R04404" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "SEC16 homolog A (S. cerevisiae etc.
(Sec16a, Inpp5e, Pharbin etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 146 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29688" kegg_name "rno:29688" kegg_reaction0 "rn:R03434" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "multiple inositol-polyphosphate phosphatase 1
(Minpp1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 147 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2630.0 y 2000.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171088+rno:287533+rno:365382" kegg_name "rno:171088 rno:287533 rno:365382" kegg_reaction0 "rn:R03430" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-5-phosphatase J etc.
(Inpp5j, Inpp, Pib5pa, Pipp etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 148 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:308451+rno:54260+rno:81677" kegg_name "rno:308451 rno:54260 rno:81677" kegg_reaction0 "rn:R03433" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol-trisphosphate 3-kinase etc.
(Itpkc etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 149 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.0 y 2060.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:500709" kegg_name "rno:500709" kegg_reaction0 "rn:R03428" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol-tetrakisphosphate 1-kinase (EC:2.7.1.-
(Itpk1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 150 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2560.0 y 2110.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:500709" kegg_name "rno:500709" kegg_reaction0 "rn:R03429" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol-tetrakisphosphate 1-kinase (EC:2.7.1.-
(Itpk1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 151 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2880.05 y 1850.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171088+rno:287533+rno:365382" kegg_name "rno:171088 rno:287533 rno:365382" kegg_reaction0 "rn:R03394" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-5-phosphatase J etc.
(Inpp5j, Inpp, Pib5pa, Pipp etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 152 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2690.0 y 2110.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316376" kegg_name "rno:316376" kegg_reaction0 "rn:R03427" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-1-phosphatase
(Inpp1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 153 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2980.05 y 1900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316376" kegg_name "rno:316376" kegg_reaction0 "rn:R03393" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-1-phosphatase
(Inpp1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 154 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2810.0 y 2110.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116699+rno:80849" kegg_name "rno:116699 rno:80849" kegg_reaction0 "rn:R04372" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-4-phosphatase, type II etc.
(Inpp4b etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 155 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2870.05 y 2060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290651" kegg_name "rno:290651" kegg_reaction0 "rn:R07324" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol-3-phosphate synthase 1
(Isyna1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 156 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2980.05 y 2040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:282636+rno:312952+rno:83523" kegg_name "rno:282636 rno:312952 rno:83523" kegg_reaction0 "rn:R01186" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol (myo)-1(or 4)-monophosphatase etc.
(Impa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 157 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2920.0 y 2110.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:282636+rno:312952+rno:83523" kegg_name "rno:282636 rno:312952 rno:83523" kegg_reaction0 "rn:R01187" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol (myo)-1(or 4)-monophosphatase etc.
(Impa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 158 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.0 y 1650.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114554+rno:305419+rno:64161+rno:81747" kegg_name "rno:114554 rno:305419 rno:64161 rno:81747" kegg_reaction0 "rn:R03361" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatidylinositol 4-kinase type 2 alpha etc.
(Pi4k2a, Pi4KII etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 159 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2550.0 y 1780.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:309419+rno:314641+rno:365865+rno:687758" kegg_name "rno:309419 rno:314641 rno:365865 rno:687758" kegg_reaction0 "rn:R03469" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatidylinositol-4-phosphate 5-kinase, type I, beta etc.
(Pip5k1b, Pip5k1a etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 160 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65052" kegg_name "rno:65052" kegg_reaction0 "rn:R03362" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoinositide-3-kinase, class 3
(Pik3c3)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 161 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288762" kegg_name "rno:288762" kegg_reaction0 "rn:R03363" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "myotubularin 1
(Mtm1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 162 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.05 y 1850.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114633+rno:140693+rno:24654+rno:24655+rno:25031+rno:25738+rno:287745+rno:29322+rno:29337+rno:497197+rno:85240" kegg_name "rno:114633 rno:140693 rno:24654 rno:24655 rno:25031 rno:25738 rno:287745 rno:29322 rno:29337 rno:497197 rno:85240" kegg_reaction0 "rn:R03435" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase C, epsilo etc.
(Plce1, Plce etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 163 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2580.05 y 1960.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:306808" kegg_name "rno:306808" kegg_reaction0 "rn:R05202" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol 1,3,4,5,6-pentakisphosphate 2-kinase
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0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01204" kegg_name "cpd:C01204" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 166 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1850.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01245" kegg_name "cpd:C01245" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 167 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2630.0 y 2110.0 w 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"false" transLevel 0.0 ] ] node [ id 169 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2470.0 y 2110.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04477" kegg_name "cpd:C04477" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 170 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2760.0 y 2110.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04063" kegg_name "cpd:C04063" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color 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kegg_name "cpd:C04006" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 173 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2980.05 y 1960.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03546" kegg_name "cpd:C03546" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 174 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1580.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04549" kegg_name "cpd:C04549" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 175 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2580.05 y 1850.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04637" kegg_name "cpd:C04637" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 176 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2580.05 y 1720.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01277" kegg_name "cpd:C01277" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 177 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3140.05 y 2100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00691" kegg_name "cpd:C00691" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 178 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3300.05 y 2100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04287" kegg_name "cpd:C04287" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 179 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3460.05 y 2100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16737" kegg_name "cpd:C16737" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 180 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3460.05 y 1980.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06892" kegg_name "cpd:C06892" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 181 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3460.05 y 1840.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06893" kegg_name "cpd:C06893" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 182 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2520.05 y 1940.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192260" kegg_name "rno:192260" kegg_reaction0 "rn:R01802" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "CDP-diacylglycerol--inositol 3-phosphatidyltransferase
(Cdipt, Pis, Pis1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 183 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1720.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11554" kegg_name "cpd:C11554" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 184 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116699+rno:80849" kegg_name "rno:116699 rno:80849" kegg_reaction0 "rn:R07299" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol polyphosphate-4-phosphatase, type II etc.
(Inpp4b etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 185 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.05 y 1720.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116720+rno:289021+rno:361632" kegg_name "rno:116720 rno:289021 rno:361632" kegg_reaction0 "rn:R05795" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoinositide-3-kinase, class 2, gamma polypeptide etc.
(Pik3c2g etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 186 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1420.05 y 1520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65030" kegg_name "rno:65030" kegg_reaction0 "rn:R07111" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "epoxide hydrolase 2, cytoplasmic
(Ephx2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 187 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1420.0 y 1600.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65030" kegg_name "rno:65030" kegg_reaction0 "rn:R07110" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "epoxide hydrolase 2, cytoplasmic
(Ephx2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 188 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1420.05 y 1680.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65030" kegg_name "rno:65030" kegg_reaction0 "rn:R07109" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "epoxide hydrolase 2, cytoplasmic
(Ephx2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 189 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1080.05 y 1800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65030" kegg_name "rno:65030" kegg_reaction0 "rn:R07108" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "epoxide hydrolase 2, cytoplasmic
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"no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14822" kegg_name "cpd:C14822" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 192 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1320.05 y 1360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14823" kegg_name "cpd:C14823" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 193 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1320.05 y 1240.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14776" kegg_name "cpd:C14776" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 194 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 920.0 y 1190.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14748" kegg_name "cpd:C14748" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 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(Cyp2j3, Cyp2j9 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 210 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 580.05 y 1620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:313375+rno:502969+rno:65210" kegg_name "rno:313375 rno:502969 rno:65210" kegg_reaction0 "rn:R07045" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily j, polypeptide etc.
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(Cyp2c22, Cyp2c70 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 213 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1320.0 y 1410.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:266604" kegg_name "rno:266604" kegg_reaction0 "rn:R07053" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 15-lipoxygenase, type B
(Alox15b)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 214 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1460.0 y 1410.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287425" kegg_name "rno:287425" kegg_reaction0 "rn:R07038" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 12-lipoxygenase, 12R type (EC:1.13.11.-
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(Cyp2u1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 217 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1000.0 y 1160.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:266689+rno:286904+rno:286905+rno:290623+rno:299566+rno:500801+rno:503122+rno:56266" kegg_name "rno:266689 rno:286904 rno:286905 rno:290623 rno:299566 rno:500801 rno:503122 rno:56266" kegg_reaction0 "rn:R07041" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 4, subfamily f, polypeptide etc.
(Cyp4f6 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 218 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1000.05 y 1280.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25086" kegg_name "rno:25086" kegg_reaction0 "rn:R07046" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily e, polypeptide 1
(Cyp2e1, Cyp2e)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 219 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1000.0 y 1190.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24306+rno:266674+rno:298423+rno:50549" kegg_name "rno:24306 rno:266674 rno:298423 rno:50549" kegg_reaction0 "rn:R07041" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 4, subfamily a, polypeptide etc.
(Cyp4a2, Cyp4a11 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 220 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1500.05 y 1440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287454+rno:303252" kegg_name "rno:287454 rno:303252" kegg_reaction0 "rn:R01596" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 12-lipoxygenase etc.
(Alox12, 12-LO etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 221 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.0 y 1470.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:266604+rno:81639" kegg_name "rno:266604 rno:81639" kegg_reaction0 "rn:R01593" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 15-lipoxygenase, type B etc.
(Alox15b etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 222 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 600.05 y 1440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24693+rno:29527" kegg_name "rno:24693 rno:29527" kegg_reaction0 "rn:R00073" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "prostaglandin-endoperoxide synthase etc.
(Ptgs1, Cox-3, Cox1, Cox3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 223 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1260.05 y 1290.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192259+rno:24653+rno:289733+rno:29354+rno:29359+rno:29387+rno:29526+rno:296091+rno:29692+rno:298579+rno:311341+rno:360426+rno:362039+rno:367415+rno:690388+rno:691813+rno:691905+rno:691907" kegg_name "rno:192259 rno:24653 rno:289733 rno:29354 rno:29359 rno:29387 rno:29526 rno:296091 rno:29692 rno:298579 rno:311341 rno:360426 rno:362039 rno:367415 rno:690388 rno:691813 rno:691905 rno:691907" kegg_reaction0 "rn:R01317" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phospholipase B etc.
(Plb1, Phlpb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 224 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 800.05 y 1360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25290" kegg_name "rno:25290" kegg_reaction0 "rn:R03058" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 5-lipoxygenase
(Alox5, LOX5A)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 225 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1000.05 y 1360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25290" kegg_name "rno:25290" kegg_reaction0 "rn:R01595" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 5-lipoxygenase
(Alox5, LOX5A)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 226 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 640.05 y 1360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:299732" kegg_name "rno:299732" kegg_reaction0 "rn:R03057" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "leukotriene A4 hydrolase
(Lta4h)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 227 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 1320.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114097" kegg_name "rno:114097" kegg_reaction0 "rn:R03059" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "leukotriene C4 synthase
(Ltc4s)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 228 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 1220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116568+rno:156275+rno:29566+rno:408206" kegg_name "rno:116568 rno:156275 rno:29566 rno:408206" kegg_reaction0 "rn:R03867" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "gamma-glutamyltransferase etc.
(Ggt1, GGLUT, Ggt, Ggtp etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 229 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 1440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24693+rno:29527" kegg_name "rno:24693 rno:29527" kegg_reaction0 "rn:R01590" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "prostaglandin-endoperoxide synthase etc.
(Ptgs1, Cox-3, Cox1, Cox3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 230 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.05 y 1480.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25527" kegg_name "rno:25527" kegg_reaction0 "rn:R02267" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "prostaglandin I2 (prostacyclin) synthase
(Ptgis, PGIS)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 231 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 300.05 y 1440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311865+rno:362809+rno:367808+rno:59103" kegg_name "rno:311865 rno:362809 rno:367808 rno:59103" kegg_reaction0 "rn:R02265" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "prostaglandin E synthase etc.
(Ptges2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 232 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.05 y 1320.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24886" kegg_name "rno:24886" kegg_reaction0 "rn:R02268" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "thromboxane A synthase 1, platelet
(Tbxas1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 233 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 340.0 y 1480.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25526+rno:58962" kegg_name "rno:25526 rno:58962" kegg_reaction0 "rn:R02266" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "prostaglandin D2 synthase etc.
(Ptgds, PH2DISO etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 234 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 230.0 y 1400.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29224+rno:304078+rno:688320" kegg_name "rno:29224 rno:304078 rno:688320" kegg_reaction0 "rn:R02581" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "carbonyl reductase etc.
(Cbr1, Cbr etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 235 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.0 y 1260.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02198" kegg_name "cpd:C02198" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 236 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 560.05 y 1360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02165" kegg_name "cpd:C02165" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 237 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 1360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00909" kegg_name "cpd:C00909" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 238 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 920.05 y 1360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05356" kegg_name "cpd:C05356" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 239 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 1260.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02166" kegg_name "cpd:C02166" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 240 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.0 y 1540.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01312" kegg_name "cpd:C01312" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 241 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 230.05 y 1440.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00584" kegg_name "cpd:C00584" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" 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"cpd:C00427" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 244 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 300.05 y 1600.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05957" kegg_name "cpd:C05957" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 245 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 1520.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05966" kegg_name "cpd:C05966" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 246 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1600.05 y 1440.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05965" kegg_name "cpd:C05965" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 247 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ 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"http://www.kegg.jp/dbget-bin/www_bget?C05958" kegg_name "cpd:C05958" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 253 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 340.0 y 1540.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00696" kegg_name "cpd:C00696" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 254 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 140.05 y 1520.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05953" kegg_name "cpd:C05953" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 255 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 140.05 y 1600.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05955" kegg_name "cpd:C05955" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 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fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 258 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.05 y 1680.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05962" kegg_name "cpd:C05962" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 259 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 980.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06462" kegg_name "cpd:C06462" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 260 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1000.0 y 1250.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:313375+rno:502969+rno:65210" kegg_name "rno:313375 rno:502969 rno:65210" kegg_reaction0 "rn:R07046" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily j, polypeptide etc.
(Cyp2j3, Cyp2j9 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 261 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 340.05 y 1340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:362676" kegg_name "rno:362676" kegg_reaction0 "rn:R09506" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "family with sequence similarity 213, member B
(Fam213b, RGD1308251)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 262 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7480.0 y 4180.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:367323" kegg_name "rno:367323" kegg_reaction0 "rn:R03004" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "nudix (nucleoside diphosphate linked moiety X)-type motif 12
(Nudt12)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 263 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7420.05 y 4060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:293504" kegg_name "rno:293504" kegg_reaction0 "rn:R03348" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "quinolinate phosphoribosyltransferase
(Qprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 264 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7480.05 y 4140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:54410+rno:85496" kegg_name "rno:54410 rno:85496" kegg_reaction0 "rn:R03004" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleotide pyrophosphatase/phosphodiesterase etc.
(Enpp3, Npp3, RB13-6 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 265 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7340.05 y 4140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315085" kegg_name "rno:315085" kegg_reaction0 "rn:R01724" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "nicotinate phosphoribosyltransferase domain containing 1
(Naprt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 266 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7280.05 y 4360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:300691" kegg_name "rno:300691" kegg_reaction0 "rn:R01269" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "nicotinamide N-methyltransferase
(Nnmt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 267 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.0 y 4720.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100125370" kegg_name "rno:100125370" kegg_reaction0 "rn:R00104" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "AD kinase
(Nadk)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 268 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.0 y 4780.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:310378" kegg_name "rno:310378" kegg_reaction0 "rn:R00112" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "nicotinamide nucleotide transhydrogenase
(Nnt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 269 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7280.05 y 4500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316421+rno:316424+rno:493909+rno:54349" kegg_name "rno:316421 rno:316424 rno:493909 rno:54349" kegg_reaction0 "rn:R08408" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde oxidase 3-like etc.
(Aox3l1, Aox2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 270 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7420.05 y 4500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316421+rno:316424+rno:493909+rno:54349" kegg_name "rno:316421 rno:316424 rno:493909 rno:54349" kegg_reaction0 "rn:R04085" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde oxidase 3-like etc.
(Aox3l1, Aox2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 271 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7160.05 y 3920.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06178" kegg_name "cpd:C06178" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 272 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7420.05 y 4140.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01185" kegg_name "cpd:C01185" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 273 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7280.05 y 4140.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00253" kegg_name "cpd:C00253" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 274 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7280.05 y 4440.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02918" kegg_name "cpd:C02918" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 275 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6400.05 y 4000.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05840" kegg_name "cpd:C05840" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 276 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7420.05 y 4580.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05843" kegg_name "cpd:C05843" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 277 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7280.05 y 4580.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05842" kegg_name "cpd:C05842" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 278 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5680.05 y 2000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24240" kegg_name "rno:24240" kegg_reaction0 "rn:R01397" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
(Cad)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 279 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4760.05 y 1840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24240" kegg_name "rno:24240" kegg_reaction0 "rn:R01993" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
(Cad)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 280 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4760.05 y 1480.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288051" kegg_name "rno:288051" kegg_reaction0 "rn:R01870" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "uridine monophosphate synthetase
(Umps)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 281 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5180.05 y 900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:360992" kegg_name "rno:360992" kegg_reaction0 "rn:R00438" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "polyribonucleotide nucleotidyltransferase 1
(Pnpt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 282 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5080.05 y 840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363176+rno:117017+rno:288588+rno:289561+rno:291795+rno:292778+rno:300088+rno:301246+rno:306012+rno:310685+rno:311487+rno:313245+rno:361102+rno:361365+rno:361640+rno:361784+rno:362728+rno:362858+rno:363633+rno:364834+rno:366277+rno:498109+rno:502374+rno:681193+rno:685465+rno:690254+rno:690966+rno:83503+rno:83581+rno:83582" kegg_name "rno:100363176 rno:117017 rno:288588 rno:289561 rno:291795 rno:292778 rno:300088 rno:301246 rno:306012 rno:310685 rno:311487 rno:313245 rno:361102 rno:361365 rno:361640 rno:361784 rno:362728 rno:362858 rno:363633 rno:364834 rno:366277 rno:498109 rno:502374 rno:681193 rno:685465 rno:690254 rno:690966 rno:83503 rno:83581 rno:83582" kegg_reaction0 "rn:R00443" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K03009 DNA-directed RNA polymerases I, II, and III subunit RPAB etc.
(DEFINITION mCG145114-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 283 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R00156" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 284 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 980.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:26956" kegg_name "rno:26956" kegg_reaction0 "rn:R00157" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenylate kinase 3
(Ak3)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 285 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 980.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298410+rno:314004" kegg_name "rno:298410 rno:314004" kegg_reaction0 "rn:R00158" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "cytidine monophosphate (UMP-CMP) kinase etc.
(Cmpk1, Cmpk, RGD1310116 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 286 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4900.05 y 1080.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:313560+rno:619580" kegg_name "rno:313560 rno:619580" kegg_reaction0 "rn:R00571" kegg_reaction1 "rn:R00573" kegg_reaction_type0 "irreversible" kegg_reaction_type1 "irreversible" kegg_type "gene" ] label "CTP synthase etc.
(Ctps etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 287 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1020.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00159" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 288 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 1020.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:246272+rno:314312+rno:361063+rno:85260" kegg_name "rno:246272 rno:314312 rno:361063 rno:85260" kegg_reaction0 "rn:R00155" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "calcium activated nucleotidase etc.
(Cant1, srapy etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 289 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 1000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00155" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 290 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5510.0 y 1060.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:317237" kegg_name "rno:317237" kegg_reaction0 "rn:R00966" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae
(Uprt, RGD1564806)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 291 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.05 y 1020.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:304944+rno:311864+rno:499956" kegg_name "rno:304944 rno:311864 rno:499956" kegg_reaction0 "rn:R00964" kegg_reaction1 "rn:R00967" kegg_reaction2 "rn:R00968" kegg_reaction3 "rn:R00970" kegg_reaction4 "rn:R01549" kegg_reaction5 "rn:R01880" kegg_reaction6 "rn:R02097" kegg_reaction7 "rn:R02327" kegg_reaction8 "rn:R02332" kegg_reaction_type0 "irreversible" kegg_reaction_type1 "irreversible" kegg_reaction_type2 "irreversible" kegg_reaction_type3 "irreversible" kegg_reaction_type4 "irreversible" kegg_reaction_type5 "irreversible" kegg_reaction_type6 "irreversible" kegg_reaction_type7 "irreversible" kegg_reaction_type8 "irreversible" kegg_type "gene" ] label "uridine-cytidine kinase etc.
(Uck2, Umpk etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 292 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.0 y 980.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R00963" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 293 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5520.05 y 1000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:289801+rno:295620" kegg_name "rno:289801 rno:295620" kegg_reaction0 "rn:R01876" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "uridine phosphorylase etc.
(Upp1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 294 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5000.05 y 1100.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363176+rno:117017+rno:288588+rno:289561+rno:291795+rno:292778+rno:300088+rno:301246+rno:306012+rno:310685+rno:311487+rno:313245+rno:361102+rno:361365+rno:361640+rno:361784+rno:362728+rno:362858+rno:363633+rno:364834+rno:366277+rno:498109+rno:502374+rno:681193+rno:685465+rno:690254+rno:690966+rno:83503+rno:83581+rno:83582" kegg_name "rno:100363176 rno:117017 rno:288588 rno:289561 rno:291795 rno:292778 rno:300088 rno:301246 rno:306012 rno:310685 rno:311487 rno:313245 rno:361102 rno:361365 rno:361640 rno:361784 rno:362728 rno:362858 rno:363633 rno:364834 rno:366277 rno:498109 rno:502374 rno:681193 rno:685465 rno:690254 rno:690966 rno:83503 rno:83581 rno:83582" kegg_reaction0 "rn:R00442" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K03009 DNA-directed RNA polymerases I, II, and III subunit RPAB etc.
(DEFINITION mCG145114-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 295 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5380.0 y 1160.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:360992" kegg_name "rno:360992" kegg_reaction0 "rn:R00440" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "polyribonucleotide nucleotidyltransferase 1
(Pnpt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 296 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00569" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 297 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1180.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R00570" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 298 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 1180.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00514" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 299 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 1220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298410+rno:314004" kegg_name "rno:298410 rno:314004" kegg_reaction0 "rn:R00512" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "cytidine monophosphate (UMP-CMP) kinase etc.
(Cmpk1, Cmpk, RGD1310116 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 300 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.05 y 1220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:304944+rno:311864+rno:499956" kegg_name "rno:304944 rno:311864 rno:499956" kegg_reaction0 "rn:R00513" kegg_reaction1 "rn:R00516" kegg_reaction2 "rn:R00517" kegg_reaction3 "rn:R00962" kegg_reaction4 "rn:R01548" kegg_reaction5 "rn:R02091" kegg_reaction6 "rn:R02096" kegg_reaction7 "rn:R02371" kegg_reaction8 "rn:R02372" kegg_reaction_type0 "irreversible" kegg_reaction_type1 "irreversible" kegg_reaction_type2 "irreversible" kegg_reaction_type3 "irreversible" kegg_reaction_type4 "irreversible" kegg_reaction_type5 "irreversible" kegg_reaction_type6 "irreversible" kegg_reaction_type7 "irreversible" kegg_reaction_type8 "irreversible" kegg_type "gene" ] label "uridine-cytidine kinase etc.
(Uck2, Umpk etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 301 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.05 y 1180.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R00511" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 302 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 1100.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:362638" kegg_name "rno:362638" kegg_reaction0 "rn:R01878" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytidine deaminase
(Cda)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 303 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4970.0 y 1380.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R02326" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 304 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5040.05 y 1470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100362333+rno:246327+rno:289758+rno:293144+rno:298098+rno:299112+rno:301323+rno:304573+rno:361698+rno:362385+rno:59294+rno:85241+rno:85242" kegg_name "rno:100362333 rno:246327 rno:289758 rno:293144 rno:298098 rno:299112 rno:301323 rno:304573 rno:361698 rno:362385 rno:59294 rno:85241 rno:85242" kegg_reaction0 "rn:R00377" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K02326 DNA polymerase epsilon subunit etc.
(DEFINITION DNA-directed DNA polymerase epsilon 3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 305 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5170.0 y 1380.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298410+rno:314004" kegg_name "rno:298410 rno:314004" kegg_reaction0 "rn:R01665" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytidine monophosphate (UMP-CMP) kinase etc.
(Cmpk1, Cmpk, RGD1310116 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 306 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5260.05 y 1490.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290741" kegg_name "rno:290741" kegg_reaction0 "rn:R01663" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dCMP deaminase
(Dctd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 307 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5080.05 y 1620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:497778" kegg_name "rno:497778" kegg_reaction0 "rn:R02100" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "deoxyuridine triphosphatase
(Dut, Dutp, PIP4)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 308 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R02331" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 309 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301622" kegg_name "rno:301622" kegg_reaction0 "rn:R02098" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "deoxythymidylate kinase (thymidylate kinase)
(Dtymk)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 310 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5260.05 y 1660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29261" kegg_name "rno:29261" kegg_reaction0 "rn:R02101" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "thymidylate synthetase
(Tyms)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 311 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5200.05 y 1680.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100362333+rno:246327+rno:289758+rno:293144+rno:298098+rno:299112+rno:301323+rno:304573+rno:361698+rno:362385+rno:59294+rno:85241+rno:85242" kegg_name "rno:100362333 rno:246327 rno:289758 rno:293144 rno:298098 rno:299112 rno:301323 rno:304573 rno:361698 rno:362385 rno:59294 rno:85241 rno:85242" kegg_reaction0 "rn:R00378" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K02326 DNA polymerase epsilon subunit etc.
(DEFINITION DNA-directed DNA polymerase epsilon 3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 312 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5040.0 y 1910.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R02093" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 313 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5100.05 y 1910.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R02095" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 314 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5100.05 y 1800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301622" kegg_name "rno:301622" kegg_reaction0 "rn:R02094" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "deoxythymidylate kinase (thymidylate kinase)
(Dtymk)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 315 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5040.05 y 1800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R02092" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 316 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.0 y 1710.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R01569" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 317 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.0 y 1770.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24834+rno:291824" kegg_name "rno:24834 rno:291824" kegg_reaction0 "rn:R01567" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "thymidine kinase 1, soluble etc.
(Tk1, Tk etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 318 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4820.05 y 1740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315219" kegg_name "rno:315219" kegg_reaction0 "rn:R01570" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "thymidine phosphorylase
(Tymp, Ecgf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 319 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4610.0 y 1740.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81656" kegg_name "rno:81656" kegg_reaction0 "rn:R01415" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "dihydropyrimidine dehydrogenase
(Dpyd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 320 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4450.0 y 1740.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65135" kegg_name "rno:65135" kegg_reaction0 "rn:R03055" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "dihydropyrimidinase
(Dpys)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 321 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4310.0 y 1740.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116593" kegg_name "rno:116593" kegg_reaction0 "rn:R04666" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ureidopropionase, beta
(Upb1, Bup1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 322 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4760.0 y 1630.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65156" kegg_name "rno:65156" kegg_reaction0 "rn:R01868" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "dihydroorotate dehydrogenase (quinone)
(Dhodh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 323 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5100.05 y 920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288051" kegg_name "rno:288051" kegg_reaction0 "rn:R00965" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "uridine monophosphate synthetase
(Umps)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 324 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4980.05 y 1060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311422" kegg_name "rno:311422" kegg_reaction0 "rn:R00662" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
(Itpa)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 325 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5080.05 y 1660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311422" kegg_name "rno:311422" kegg_reaction0 "rn:R02100" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
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rno:25011 rno:25086 rno:252931 rno:25642 rno:266682 rno:29277 rno:29298 rno:293989 rno:313375 rno:502969 rno:65210 rno:83790" kegg_reaction0 "rn:R07055" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 3, subfamily a, polypeptide etc.
(Cyp3a9, Cyp3a13, P450olf3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 386 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 890.0 y 1900.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04717" kegg_name "cpd:C04717" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 387 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 760.0 y 1900.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14825" kegg_name "cpd:C14825" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 388 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 680.05 y 1780.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171352+rno:171518+rno:171521+rno:24297+rno:25011+rno:25086+rno:252931+rno:25642+rno:266682+rno:29277+rno:29298+rno:293989+rno:313375+rno:502969+rno:65210+rno:83790" kegg_name "rno:171352 rno:171518 rno:171521 rno:24297 rno:25011 rno:25086 rno:252931 rno:25642 rno:266682 rno:29277 rno:29298 rno:293989 rno:313375 rno:502969 rno:65210 rno:83790" kegg_reaction0 "rn:R07056" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 3, subfamily a, polypeptide etc.
(Cyp3a9, Cyp3a13, P450olf3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 389 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 960.05 y 1900.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14827" kegg_name "cpd:C14827" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 390 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 890.0 y 1810.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81639" kegg_name "rno:81639" kegg_reaction0 "rn:R03626" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arachidonate 15-lipoxygenase
(Alox15, 12-LOX, Alox12, Alox12l)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 391 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1560.05 y 1540.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192259+rno:24653+rno:289733+rno:29354+rno:29359+rno:29387+rno:29526+rno:296091+rno:29692+rno:298579+rno:311341+rno:360426+rno:362039+rno:367415+rno:690388+rno:691813+rno:691905+rno:691907" kegg_name "rno:192259 rno:24653 rno:289733 rno:29354 rno:29359 rno:29387 rno:29526 rno:296091 rno:29692 rno:298579 rno:311341 rno:360426 rno:362039 rno:367415 rno:690388 rno:691813 rno:691905 rno:691907" kegg_reaction0 "rn:R07064" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase B etc.
(Plb1, Phlpb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 392 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 580.0 y 1780.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C14826" kegg_name "cpd:C14826" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 393 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3040.05 y 2840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65984" kegg_name "rno:65984" kegg_reaction0 "rn:R01357" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetoacetyl-CoA synthetase
(Aacs)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 394 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2020.05 y 3120.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:246263+rno:24763+rno:353317+rno:361637" kegg_name "rno:246263 rno:24763 rno:353317 rno:361637" kegg_reaction0 "rn:R01176" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acyl-CoA synthetase medium-chain family member 2A etc.
(Acsm2a, Acsm2, KS etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 395 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4140.0 y 4090.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:314196" kegg_name "rno:314196" kegg_reaction0 "rn:R03534" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "L-2-hydroxyglutarate dehydrogenase
(L2hgdh, RGD1306250)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 396 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1900.0 y 3260.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02527" kegg_name "cpd:C02527" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 397 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2020.0 y 3310.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00246" kegg_name "cpd:C00246" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 398 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4200.05 y 4090.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02630" kegg_name "cpd:C02630" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 399 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.0 y 2580.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00473" kegg_name "cpd:C00473" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 400 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.0 y 2690.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100145871+rno:171178+rno:24172+rno:29646+rno:310903" kegg_name "rno:100145871 rno:171178 rno:24172 rno:29646 rno:310903" kegg_reaction0 "rn:R02124" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "alcohol dehydrogenase 5 (class III), chi polypeptide etc.
(Adh5 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 401 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 720.05 y 2740.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00376" kegg_name "cpd:C00376" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 402 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 560.05 y 2840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114106" kegg_name "rno:114106" kegg_reaction0 "rn:R00032" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "beta-carotene 15,15'-monooxygenase 1
(Bcmo1, Bcdo)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 403 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 420.05 y 2840.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02094" kegg_name "cpd:C02094" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 404 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 2740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116676+rno:24188" kegg_name "rno:116676 rno:24188" kegg_reaction0 "rn:R02123" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde dehydrogenase 1 family, member A etc.
(Aldh1a2, Raldh-2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 405 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 860.05 y 2740.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00777" kegg_name "cpd:C00777" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 406 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 580.05 y 2740.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02110" kegg_name "cpd:C02110" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 407 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.0 y 2630.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:314264+rno:353252+rno:360420+rno:362757+rno:690953" kegg_name "rno:314264 rno:353252 rno:360420 rno:362757 rno:690953" kegg_reaction0 "rn:R02124" kegg_reaction1 "rn:R08379" kegg_reaction_type0 "reversible" kegg_reaction_type1 "reversible" kegg_type "gene" ] label "retinol dehydrogenase 12 (all-trans/9-cis/11-cis etc.
(Rdh12 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 408 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 660.0 y 2630.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170635+rno:266686+rno:313689" kegg_name "rno:170635 rno:266686 rno:313689" kegg_reaction0 "rn:R02124" kegg_reaction1 "rn:R08379" kegg_reaction_type0 "reversible" kegg_reaction_type1 "reversible" kegg_type "gene" ] label "dehydrogenase/reductase (SDR family) member etc.
(Dhrs9, Rdhl etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 409 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 660.0 y 2690.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:286964+rno:297805" kegg_name "rno:286964 rno:297805" kegg_reaction0 "rn:R02124" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxysteroid (17-beta) dehydrogenase etc.
(Hsd17b6, Hsd17b9 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 410 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1570.05 y 490.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "yes" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:502017" kegg_name "rno:502017" kegg_reaction0 "rn:R01009" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dolichyl-phosphate mannosyltransferase polypeptide 3
(Dpm3, RGD1561807)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 411 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1510.05 y 450.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "yes" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29640" kegg_name "rno:29640" kegg_reaction0 "rn:R01009" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
(Dpm2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 412 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1730.0 y 890.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03021" kegg_name "cpd:C03021" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 413 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1700.0 y 190.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01246" kegg_name "cpd:C01246" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 414 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1540.05 y 960.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03862" kegg_name "cpd:C03862" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 415 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1300.05 y 320.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00381" kegg_name "cpd:C00381" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 416 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1420.05 y 320.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00110" kegg_name "cpd:C00110" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 417 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1540.05 y 470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "yes" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:296394" kegg_name "rno:296394" kegg_reaction0 "rn:R01009" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
(Dpm1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 418 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1360.05 y 320.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311847" kegg_name "rno:311847" kegg_reaction0 "rn:R01018" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dolichol kinase
(Dolk, Tmem15)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 419 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 380.05 y 160.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_name "gl:G10618" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 8 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 420 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 350.05 y 640.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_name "gl:G10617" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 8 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 421 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 700.05 y 560.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_name "gl:G10614" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 8 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 422 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4240.0 y 4340.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171352+rno:252931+rno:25642+rno:266682" kegg_name "rno:171352 rno:252931 rno:25642 rno:266682" kegg_reaction0 "rn:R08276" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cytochrome P450, family 3, subfamily a, polypeptide etc.
(Cyp3a9, Cyp3a13, P450olf3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 423 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2260.05 y 2140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24300+rno:286953+rno:292728+rno:29295+rno:361523" kegg_name "rno:24300 rno:286953 rno:292728 rno:29295 rno:361523" kegg_reaction0 "rn:R08324" kegg_reaction1 "rn:R08325" kegg_reaction2 "rn:R08326" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily b, polypeptide etc.
(Cyp2b1, Cyp2b-1, Cypbe etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 424 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2320.05 y 2080.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171518+rno:171521+rno:25011+rno:29277+rno:29298+rno:293989+rno:83790" kegg_name "rno:171518 rno:171521 rno:25011 rno:29277 rno:29298 rno:293989 rno:83790" kegg_reaction0 "rn:R08324" kegg_reaction1 "rn:R08325" kegg_reaction2 "rn:R08326" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily c, polypeptide etc.
(Cyp2c22, Cyp2c70 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 425 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2360.05 y 2140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24299+rno:24894+rno:24895" kegg_name "rno:24299 rno:24894 rno:24895" kegg_reaction0 "rn:R08324" kegg_reaction1 "rn:R08325" kegg_reaction2 "rn:R08326" kegg_type "gene" ] label "cytochrome P450, family 2, subfamily a, polypeptide etc.
(Cyp2a3, Cyp2a3a, RATCYP2A3A etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 426 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4200.05 y 4400.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_name "cpd:C07888" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 8 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 427 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6460.05 y 600.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100359539+rno:299976+rno:362720+rno:685579" kegg_name "rno:100359539 rno:299976 rno:362720 rno:685579" kegg_reaction0 "rn:R02019" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K10808 ribonucleoside-diphosphate reductase subunit M etc.
(DEFINITION ribonucleotide reductase M2 polypeptide etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 428 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 1200.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C12248" kegg_name "cpd:C12248" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 429 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 1100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11821" kegg_name "cpd:C11821" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 430 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 1120.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:117544" kegg_name "rno:117544" kegg_reaction0 "rn:R01072" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosyl pyrophosphate amidotransferase
(Ppat, Atase)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 431 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4740.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288259" kegg_name "rno:288259" kegg_reaction0 "rn:R04144" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosylglycinamide formyltransferase
(Gart)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 432 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4920.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288259" kegg_name "rno:288259" kegg_reaction0 "rn:R04325" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosylglycinamide formyltransferase
(Gart)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 433 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5240.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288259" kegg_name "rno:288259" kegg_reaction0 "rn:R04208" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosylglycinamide formyltransferase
(Gart)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 434 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5920.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81643" kegg_name "rno:81643" kegg_reaction0 "rn:R04560" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
(Atic)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 435 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5740.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315150" kegg_name "rno:315150" kegg_reaction0 "rn:R04559" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenylosuccinate lyase
(Adsl, null)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 436 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:140946" kegg_name "rno:140946" kegg_reaction0 "rn:R04591" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
(Paics, Ade2h1, Airc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 437 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:140946" kegg_name "rno:140946" kegg_reaction0 "rn:R04209" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
(Paics, Ade2h1, Airc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 438 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5360.05 y 720.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:360992" kegg_name "rno:360992" kegg_reaction0 "rn:R00437" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "polyribonucleotide nucleotidyltransferase 1
(Pnpt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 439 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5200.05 y 820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100362333+rno:246327+rno:289758+rno:293144+rno:298098+rno:299112+rno:301323+rno:304573+rno:361698+rno:362385+rno:59294+rno:85241+rno:85242" kegg_name "rno:100362333 rno:246327 rno:289758 rno:293144 rno:298098 rno:299112 rno:301323 rno:304573 rno:361698 rno:362385 rno:59294 rno:85241 rno:85242" kegg_reaction0 "rn:R00375" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K02326 DNA polymerase epsilon subunit etc.
(DEFINITION DNA-directed DNA polymerase epsilon 3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 440 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5500.05 y 670.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R01137" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 441 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 600.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100359539+rno:299976+rno:362720+rno:685579" kegg_name "rno:100359539 rno:299976 rno:362720 rno:685579" kegg_reaction0 "rn:R02017" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K10808 ribonucleoside-diphosphate reductase subunit M etc.
(DEFINITION ribonucleotide reductase M2 polypeptide etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 442 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00122" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 443 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24183+rno:24184+rno:29223+rno:301115+rno:314416+rno:365985" kegg_name "rno:24183 rno:24184 rno:29223 rno:301115 rno:314416 rno:365985" kegg_reaction0 "rn:R00127" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenylate kinase etc.
(Ak1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 444 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5800.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315150" kegg_name "rno:315150" kegg_reaction0 "rn:R01083" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenylosuccinate lyase
(Adsl, null)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 445 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5940.0 y 520.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:289276+rno:684425" kegg_name "rno:289276 rno:684425" kegg_reaction0 "rn:R01135" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenylosuccinate synthase etc.
(Adss, Adss2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 446 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5860.0 y 470.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25028+rno:25095+rno:362015" kegg_name "rno:25028 rno:25095 rno:362015" kegg_reaction0 "rn:R00181" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenosine monophosphate deaminase etc.
(Ampd1, Ampd01, RATAMPD01 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 447 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5690.05 y 600.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R00183" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 448 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5720.05 y 620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25368" kegg_name "rno:25368" kegg_reaction0 "rn:R00185" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenosine kinase
(Adk, AK)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 449 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5670.05 y 700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:292072" kegg_name "rno:292072" kegg_reaction0 "rn:R00190" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenine phosphoribosyl transferase
(Aprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 450 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5500.05 y 780.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R02088" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 451 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 860.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24165" kegg_name "rno:24165" kegg_reaction0 "rn:R02556" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenosine deaminase
(Ada)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 452 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5720.05 y 960.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R02748" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 453 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6140.05 y 800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R02297" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 454 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6000.05 y 620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R01126" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 455 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5860.05 y 700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24165" kegg_name "rno:24165" kegg_reaction0 "rn:R01560" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenosine deaminase
(Ada)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 456 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6160.0 y 470.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:117533" kegg_name "rno:117533" kegg_reaction0 "rn:R01134" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "guanosine monophosphate reductase
(Gmpr, Gmpr1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 457 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:301005+rno:362329" kegg_name "rno:301005 rno:362329" kegg_reaction0 "rn:R01130" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "MP (inosine 5'-monophosphate) dehydrogenase etc.
(Impdh2, IMPD_2, IMPDH_2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 458 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6220.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:295088" kegg_name "rno:295088" kegg_reaction0 "rn:R01230" kegg_reaction1 "rn:R01231" kegg_reaction_type0 "irreversible" kegg_reaction_type1 "irreversible" kegg_type "gene" ] label "guanine monphosphate synthetase
(Gmps)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 459 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6380.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00328" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 460 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6380.05 y 550.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:246272+rno:314312+rno:361063+rno:85260" kegg_name "rno:246272 rno:314312 rno:361063 rno:85260" kegg_reaction0 "rn:R00328" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "calcium activated nucleotidase etc.
(Cant1, srapy etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 461 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5940.05 y 640.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24465" kegg_name "rno:24465" kegg_reaction0 "rn:R01132" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hypoxanthine phosphoribosyltransferase 1
(Hprt1, Hgprtase, Hprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 462 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5720.05 y 800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R01561" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 463 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6320.05 y 620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R01227" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 464 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6000.05 y 800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R01863" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 465 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6080.05 y 700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24465" kegg_name "rno:24465" kegg_reaction0 "rn:R02142" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hypoxanthine phosphoribosyltransferase 1
(Hprt1, Hgprtase, Hprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 466 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6140.05 y 620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R02719" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 467 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6230.05 y 720.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24465" kegg_name "rno:24465" kegg_reaction0 "rn:R01229" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hypoxanthine phosphoribosyltransferase 1
(Hprt1, Hgprtase, Hprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 468 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6380.05 y 490.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:303179" kegg_name "rno:303179" kegg_reaction0 "rn:R00332" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "guanylate kinase 1
(Guk1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 469 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6460.05 y 880.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R01969" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 470 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6220.05 y 880.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:83585" kegg_name "rno:83585" kegg_reaction0 "rn:R01676" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "guanine deaminase
(Gda, Cypin)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 471 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6280.05 y 3060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:246758" kegg_name "rno:246758" kegg_reaction0 "rn:R02422" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "allantoicase
(Allc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 472 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 1040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114768" kegg_name "rno:114768" kegg_reaction0 "rn:R02106" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "urate oxidase
(Uox, UOX-2, Uri, Uri2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 473 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 1140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:293613" kegg_name "rno:293613" kegg_reaction0 "rn:R06601" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "similar to transthyretin (4L369)
(RGD1309350)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 474 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6410.05 y 700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:360992" kegg_name "rno:360992" kegg_reaction0 "rn:R00439" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "polyribonucleotide nucleotidyltransferase 1
(Pnpt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 475 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6540.05 y 490.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316077+rno:613267+rno:64519" kegg_name "rno:316077 rno:613267 rno:64519" kegg_reaction0 "rn:R00335" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "ectonucleoside triphosphate diphosphohydrolase etc.
(Entpd3, NTPDase3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 476 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6540.05 y 520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R00330" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 477 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6460.0 y 730.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:303179" kegg_name "rno:303179" kegg_reaction0 "rn:R02090" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "guanylate kinase 1
(Guk1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 478 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6540.0 y 660.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171566+rno:191575+rno:58964+rno:685679+rno:83782+rno:85269" kegg_name "rno:171566 rno:191575 rno:58964 rno:685679 rno:83782 rno:85269" kegg_reaction0 "rn:R01857" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase etc.
(Nme7, Nm23-r7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 479 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6530.0 y 810.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363253+rno:287368+rno:298881+rno:312373+rno:313574+rno:360629+rno:58813" kegg_name "rno:100363253 rno:287368 rno:298881 rno:312373 rno:313574 rno:360629 rno:58813" kegg_reaction0 "rn:R01968" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K01081 5'-nucleotidase etc.
(DEFINITION 5'-nucleotidase, cytosolic II etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 480 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6320.05 y 800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R02147" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 481 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6770.05 y 680.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100363176+rno:117017+rno:288588+rno:289561+rno:291795+rno:292778+rno:300088+rno:301246+rno:306012+rno:310685+rno:311487+rno:313245+rno:361102+rno:361365+rno:361640+rno:361784+rno:362728+rno:362858+rno:363633+rno:364834+rno:366277+rno:498109+rno:502374+rno:681193+rno:685465+rno:690254+rno:690966+rno:83503+rno:83581+rno:83582" kegg_name "rno:100363176 rno:117017 rno:288588 rno:289561 rno:291795 rno:292778 rno:300088 rno:301246 rno:306012 rno:310685 rno:311487 rno:313245 rno:361102 rno:361365 rno:361640 rno:361784 rno:362728 rno:362858 rno:363633 rno:364834 rno:366277 rno:498109 rno:502374 rno:681193 rno:685465 rno:690254 rno:690966 rno:83503 rno:83581 rno:83582" kegg_reaction0 "rn:R00441" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K03009 DNA-directed RNA polymerases I, II, and III subunit RPAB etc.
(DEFINITION mCG145114-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 482 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6640.05 y 1060.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100362333+rno:246327+rno:289758+rno:293144+rno:298098+rno:299112+rno:301323+rno:304573+rno:361698+rno:362385+rno:59294+rno:85241+rno:85242" kegg_name "rno:100362333 rno:246327 rno:289758 rno:293144 rno:298098 rno:299112 rno:301323 rno:304573 rno:361698 rno:362385 rno:59294 rno:85241 rno:85242" kegg_reaction0 "rn:R00376" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K02326 DNA polymerase epsilon subunit etc.
(DEFINITION DNA-directed DNA polymerase epsilon 3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 483 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5080.05 y 420.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287420" kegg_name "rno:287420" kegg_reaction0 "rn:R04463" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosylformylglycinamidine synthase
(Pfas)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 484 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6460.0 y 470.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311422" kegg_name "rno:311422" kegg_reaction0 "rn:R00426" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
(Itpa)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 485 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6530.0 y 770.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:297389" kegg_name "rno:297389" kegg_reaction0 "rn:R01967" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "deoxyguanosine kinase
(Dguok)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 486 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6600.0 y 720.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:311422" kegg_name "rno:311422" kegg_reaction0 "rn:R01855" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
(Itpa)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 487 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5460.05 y 820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290029" kegg_name "rno:290029" kegg_reaction0 "rn:R02557" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "purine nucleoside phosphorylase
(Pnp, Np)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 488 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24183+rno:24184+rno:29223+rno:301115+rno:314416+rno:365985" kegg_name "rno:24183 rno:24184 rno:29223 rno:301115 rno:314416 rno:365985" kegg_reaction0 "rn:R01547" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenylate kinase etc.
(Ak1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 489 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6540.05 y 550.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100364062+rno:24651+rno:25630" kegg_name "rno:100364062 rno:24651 rno:25630" kegg_reaction0 "rn:R00430" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K00873 pyruvate kinase etc.
(DEFINITION M2 pyruvate kinase-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 490 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6540.0 y 700.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100364062+rno:24651+rno:25630" kegg_name "rno:100364062 rno:24651 rno:25630" kegg_reaction0 "rn:R01858" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K00873 pyruvate kinase etc.
(DEFINITION M2 pyruvate kinase-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 491 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6290.05 y 720.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:292072" kegg_name "rno:292072" kegg_reaction0 "rn:R01229" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "adenine phosphoribosyl transferase
(Aprt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 492 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5750.05 y 640.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:79127" kegg_name "rno:79127" kegg_reaction0 "rn:R00185" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "deoxycytidine kinase
(Dck)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 493 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5500.05 y 690.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100364062+rno:24651+rno:25630" kegg_name "rno:100364062 rno:24651 rno:25630" kegg_reaction0 "rn:R01138" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K00873 pyruvate kinase etc.
(DEFINITION M2 pyruvate kinase-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 494 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6000.05 y 420.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04734" kegg_name "cpd:C04734" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 495 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 900.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05512" kegg_name "cpd:C05512" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 496 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 780.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00559" kegg_name "cpd:C00559" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 497 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 780.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00360" kegg_name "cpd:C00360" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 498 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 680.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00206" kegg_name "cpd:C00206" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" 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"true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 524 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6000.0 y 470.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81643" kegg_name "rno:81643" kegg_reaction0 "rn:R01127" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
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(DEFINITION hypothetical protein LOC684055)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 527 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2810.0 y 3290.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11434" kegg_name "cpd:C11434" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 528 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2360.05 y 3260.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11435" kegg_name "cpd:C11435" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 529 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2120.0 y 3290.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11436" kegg_name "cpd:C11436" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 530 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1700.05 y 3260.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11453" kegg_name "cpd:C11453" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 531 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1380.05 y 3260.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C11811" kegg_name "cpd:C11811" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 532 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1600.05 y 3360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81727" kegg_name "rno:81727" kegg_reaction0 "rn:R02245" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mevalonate kinase
(Mvk)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 533 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 3040.05 y 3360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25675" kegg_name "rno:25675" kegg_reaction0 "rn:R02082" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "3-hydroxy-3-methylglutaryl-CoA reductase
(Hmgcr, 3H3M)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 534 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1700.05 y 3360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00418" kegg_name "cpd:C00418" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 535 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1500.05 y 3360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01107" kegg_name "cpd:C01107" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 536 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1300.05 y 3360.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01143" kegg_name "cpd:C01143" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 537 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1140.0 y 3300.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00129" kegg_name "cpd:C00129" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 538 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 900.05 y 3300.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00235" kegg_name "cpd:C00235" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 539 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 480.0 y 3430.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00448" kegg_name "cpd:C00448" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 540 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 480.05 y 3600.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00353" kegg_name "cpd:C00353" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 541 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1020.05 y 3300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:502143+rno:89784" kegg_name "rno:502143 rno:89784" kegg_reaction0 "rn:R01123" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "isopentenyl-diphosphate delta isomerase etc.
(Idi2, RGD1559783 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 542 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1240.05 y 3360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81726" kegg_name "rno:81726" kegg_reaction0 "rn:R01121" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mevalonate (diphospho) decarboxylase
(Mvd, Mvpd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 543 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1400.05 y 3360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:310645" kegg_name "rno:310645" kegg_reaction0 "rn:R03245" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphomevalonate kinase
(Pmvk)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 544 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 780.05 y 3300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291211+rno:83791" kegg_name "rno:291211 rno:83791" kegg_reaction0 "rn:R01658" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "geranylgeranyl diphosphate synthase etc.
(Ggps1, Crlf3, rGGPS1a, rGGPS1a1, rGGPS1a2, rGGPS1a3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 545 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 480.05 y 3300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291211+rno:83791" kegg_name "rno:291211 rno:83791" kegg_reaction0 "rn:R02003" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "geranylgeranyl diphosphate synthase etc.
(Ggps1, Crlf3, rGGPS1a, rGGPS1a1, rGGPS1a2, rGGPS1a3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 546 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 480.05 y 3540.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291211" kegg_name "rno:291211" kegg_reaction0 "rn:R02061" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "geranylgeranyl diphosphate synthase 1
(Ggps1, Crlf3, rGGPS1a, rGGPS1a1, rGGPS1a2, rGGPS1a3)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 547 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4800.0 y 700.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:60671" kegg_name "rno:60671" kegg_reaction0 "rn:R03184" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "gulonolactone (L-) oxidase
(Gulo)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 548 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3200.05 y 1020.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01825" kegg_name "cpd:C01825" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 549 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3200.05 y 1240.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C15926" kegg_name "cpd:C15926" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 550 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4930.0 y 700.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:60671" kegg_name "rno:60671" kegg_reaction0 "rn:R00647" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "gulonolactone (L-) oxidase
(Gulo)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 551 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4660.0 y 700.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25106" kegg_name "rno:25106" kegg_reaction0 "rn:R02933" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "regucalcin (senescence marker protein-30)
(Rgn, GNL, Rc, Reguc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 552 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4540.0 y 640.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291450+rno:29539+rno:29651+rno:298079+rno:64040+rno:65183" kegg_name "rno:291450 rno:29539 rno:29651 rno:298079 rno:64040 rno:65183" kegg_reaction0 "rn:R02957" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "aldehyde dehydrogenase 7 family, member A etc.
(Aldh7a1, antiquitin etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 553 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4380.05 y 640.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02670" kegg_name "cpd:C02670" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 554 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4690.0 y 640.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00818" kegg_name "cpd:C00818" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 555 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4740.0 y 700.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01040" kegg_name "cpd:C01040" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 556 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4870.0 y 700.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03289" kegg_name "cpd:C03289" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 557 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4640.05 y 760.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00679" kegg_name "cpd:C00679" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 558 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5080.05 y 700.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01041" kegg_name "cpd:C01041" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 559 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4760.05 y 640.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00684" kegg_name "cpd:C00684" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 560 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4880.05 y 640.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00545" kegg_name "cpd:C00545" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 561 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4880.05 y 760.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01114" kegg_name "cpd:C01114" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 562 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3200.05 y 860.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01115" kegg_name "cpd:C01115" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 563 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4060.05 y 660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:113992+rno:154516+rno:24861+rno:24862+rno:266685+rno:286954+rno:286989+rno:289533+rno:29623+rno:301595+rno:305264+rno:396527+rno:396551+rno:396552+rno:501907+rno:574523+rno:63867+rno:83808" kegg_name "rno:113992 rno:154516 rno:24861 rno:24862 rno:266685 rno:286954 rno:286989 rno:289533 rno:29623 rno:301595 rno:305264 rno:396527 rno:396551 rno:396552 rno:501907 rno:574523 rno:63867 rno:83808" kegg_reaction0 "rn:R08615" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "UDP glucuronosyltransferase 1 family, polypeptide A etc.
(Ugt1a6, UDPGT_1-6, Udpgt, Ugt1, Ugt1a7 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 564 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3600.0 y 4090.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:500536" kegg_name "rno:500536" kegg_reaction0 "rn:R01394" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "similar to novel protein (HT
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(Hao1, Gox1, XDH1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 566 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3650.05 y 3820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:680021" kegg_name "rno:680021" kegg_reaction0 "rn:R00465" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glyoxylate reductase/hydroxypyruvate reductase
(Grhpr)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 567 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3600.05 y 3900.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287115" kegg_name "rno:287115" kegg_reaction0 "rn:R01334" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoglycolate phosphatase
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(Agxt, Spat)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 576 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 3040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171133" kegg_name "rno:171133" kegg_reaction0 "rn:R01221" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glycine cleavage system protein H (aminomethyl carrier
(Gcsh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 577 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4030.0 y 4160.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290566+rno:360975" kegg_name "rno:290566 rno:360975" kegg_reaction0 "rn:R00621" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "oxoglutarate dehydrogenase-like (EC:1.2.4.- etc.
(Ogdhl etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 578 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3760.05 y 4320.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290566+rno:360975" kegg_name "rno:290566 rno:360975" kegg_reaction0 "rn:R03316" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "oxoglutarate dehydrogenase-like (EC:1.2.4.- etc.
(Ogdhl etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 579 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3560.05 y 4320.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:299201" kegg_name "rno:299201" kegg_reaction0 "rn:R02570" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
(Dlst)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 580 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4220.0 y 3970.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24479+rno:361596" kegg_name "rno:24479 rno:361596" kegg_reaction0 "rn:R00268" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "isocitrate dehydrogenase 1 (NADP+), soluble etc.
(Idh1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 581 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4130.0 y 3930.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114096+rno:25179+rno:94173" kegg_name "rno:114096 rno:25179 rno:94173" kegg_reaction0 "rn:R00709" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "isocitrate dehydrogenase 3 (NAD+) alpha etc.
(Idh3a etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 582 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4220.0 y 3850.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24479+rno:361596" kegg_name "rno:24479 rno:361596" kegg_reaction0 "rn:R01899" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "isocitrate dehydrogenase 1 (NADP+), soluble etc.
(Idh1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 583 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3560.05 y 3340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24159" kegg_name "rno:24159" kegg_reaction0 "rn:R00352" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "ATP citrate lyase
(Acly, ACL, Clatp)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 584 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3200.05 y 3960.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:157074+rno:289217+rno:298596+rno:363061" kegg_name "rno:157074 rno:289217 rno:298596 rno:363061" kegg_reaction0 "rn:R02164" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "succinate dehydrogenase complex, subunit A, flavoprotein (Fp etc.
(Sdha etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 585 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3200.05 y 3760.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24368" kegg_name "rno:24368" kegg_reaction0 "rn:R01082" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "fumarate hydratase
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(Aldh6a1, Mmsdh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 590 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3560.05 y 3300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81708" kegg_name "rno:81708" kegg_reaction0 "rn:R00740" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "aldehyde dehydrogenase 6 family, member A1
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(Qars)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 595 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2320.05 y 2000.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:292028" kegg_name "rno:292028" kegg_reaction0 "rn:R03658" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lysyl-tRNA synthetase
(Kars)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 596 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6080.05 y 4240.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02282" kegg_name "cpd:C02282" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 597 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6080.05 y 4480.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06112" kegg_name "cpd:C06112" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 598 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6800.05 y 4720.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02656" kegg_name "cpd:C02656" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 599 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6640.05 y 4720.05 w 5.0 h 5.0 fill 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fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 603 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6180.05 y 4620.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00120" kegg_name "cpd:C00120" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 604 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6340.05 y 4520.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05552" kegg_name "cpd:C05552" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 605 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6340.05 y 4620.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05921" kegg_name "cpd:C05921" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 606 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6180.05 y 4520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:306262" kegg_name "rno:306262" kegg_reaction0 "rn:R01077" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "biotinidase
(Btd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 607 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6500.05 y 4520.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100360464+rno:317409" kegg_name "rno:100360464 rno:317409" kegg_reaction0 "rn:R04869" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adipocyte-related X-chromosome expressed sequence etc.
(Arxes2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 608 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.0 y 3210.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192272+rno:26759+rno:29725+rno:314304+rno:503049+rno:50559+rno:681337" kegg_name "rno:192272 rno:26759 rno:29725 rno:314304 rno:503049 rno:50559 rno:681337" kegg_reaction0 "rn:R01274" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acyl-CoA thioesterase etc.
(Acot2, Mte1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 609 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4540.05 y 2820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291314+rno:308993" kegg_name "rno:291314 rno:308993" kegg_reaction0 "rn:R03595" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "selenophosphate synthetase etc.
(Sephs1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 610 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4420.05 y 2820.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01528" kegg_name "cpd:C01528" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 611 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4640.05 y 2820.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05172" kegg_name "cpd:C05172" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 612 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4420.05 y 3020.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05688" kegg_name "cpd:C05688" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 613 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4420.05 y 2920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:363285" kegg_name "rno:363285" kegg_reaction0 "rn:R03599" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "selenocysteine lyase
(Scly)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 614 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5480.05 y 3700.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06231" kegg_name "cpd:C06231" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 615 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5480.05 y 3600.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06442" kegg_name "cpd:C06442" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 616 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5480.05 y 3500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03283" kegg_name "cpd:C03283" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 617 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5860.0 y 2970.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81508" kegg_name "rno:81508" kegg_reaction0 "rn:R02821" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "betaine-homocysteine S-methyltransferase
(Bhmt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 618 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5140.0 y 2790.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24792" kegg_name "rno:24792" kegg_reaction0 "rn:R00588" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "alanine-glyoxylate aminotransferase
(Agxt, Spat)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 619 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4020.05 y 2160.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:58835" kegg_name "rno:58835" kegg_reaction0 "rn:R01513" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phosphoglycerate dehydrogenase
(Phgdh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 620 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 2970.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:245961" kegg_name "rno:245961" kegg_reaction0 "rn:R01565" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dimethylglycine dehydrogenase
(Dmgdh, Me2GlyDH)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 621 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5820.05 y 3040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24250" kegg_name "rno:24250" kegg_reaction0 "rn:R01290" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cystathionine beta synthase
(Cbs)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 622 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 2830.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:688286" kegg_name "rno:688286" kegg_reaction0 "rn:R06171" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K01620 threonine aldolase [
(DEFINITION similar to threonine aldolase 1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 623 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6000.05 y 2800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81660" kegg_name "rno:81660" kegg_reaction0 "rn:R00565" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Gatm)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 624 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4580.05 y 2160.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:293820" kegg_name "rno:293820" kegg_reaction0 "rn:R04173" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phosphoserine aminotransferase 1
(Psat1, Psa1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 625 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5480.0 y 2900.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:303272" kegg_name "rno:303272" kegg_reaction0 "rn:R00610" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "pipecolic acid oxidase
(Pipox)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 626 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5450.0 y 2930.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114123" kegg_name "rno:114123" kegg_reaction0 "rn:R00611" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "sarcosine dehydrogenase
(Sardh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 627 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4740.05 y 2360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:304429" kegg_name "rno:304429" kegg_reaction0 "rn:R00582" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoserine phosphatase
(Psph)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 628 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5160.0 y 2820.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287379+rno:299857" kegg_name "rno:287379 rno:299857" kegg_reaction0 "rn:R00945" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "serine hydroxymethyltransferase 1 (soluble etc.
(Shmt1, LRRGT00032, Shmt, mShmt etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 629 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5380.0 y 2940.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:688286" kegg_name "rno:688286" kegg_reaction0 "rn:R00751" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "RTHOLOGY K01620 threonine aldolase [
(DEFINITION similar to threonine aldolase 1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 630 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5350.05 y 3380.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114027" kegg_name "rno:114027" kegg_reaction0 "rn:R00366" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "-amino-acid oxidase
(Dao, Dao1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 631 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4400.05 y 2740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25044" kegg_name "rno:25044" kegg_reaction0 "rn:R00220" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "serine dehydratase
(Sds, RATSDHE1, SDH2, Sdh, Sdhe1, TDH)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 632 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5240.0 y 2950.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:309312" kegg_name "rno:309312" kegg_reaction0 "rn:R03425" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glycine dehydrogenase (decarboxylating)
(Gldc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 633 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5240.05 y 3440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:306586" kegg_name "rno:306586" kegg_reaction0 "rn:R04125" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aminomethyltransferase
(Amt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 634 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5510.0 y 2930.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25134" kegg_name "rno:25134" kegg_reaction0 "rn:R00367" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glycine N-methyltransferase
(Gnmt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 635 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5910.0 y 2970.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00719" kegg_name "cpd:C00719" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 636 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5780.05 y 2970.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01026" kegg_name "cpd:C01026" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 637 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5780.05 y 2830.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05519" kegg_name "cpd:C05519" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 638 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4400.05 y 2160.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03232" kegg_name "cpd:C03232" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 639 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5200.0 y 3340.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01102" kegg_name "cpd:C01102" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 640 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5240.0 y 3030.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01242" kegg_name "cpd:C01242" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 641 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5560.05 y 2700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24250" kegg_name "rno:24250" kegg_reaction0 "rn:R00891" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cystathionine beta synthase
(Cbs)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 642 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4680.05 y 3740.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24792+rno:83784" kegg_name "rno:24792 rno:83784" kegg_reaction0 "rn:R00372" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "alanine-glyoxylate aminotransferase etc.
(Agxt, Spat etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 643 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 3700.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C19929" kegg_name "cpd:C19929" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 644 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5120.05 y 3860.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25375+rno:266603+rno:309147" kegg_name "rno:25375 rno:266603 rno:309147" kegg_reaction0 "rn:R02536" kegg_reaction1 "rn:R02537" kegg_reaction_type0 "reversible" kegg_reaction_type1 "reversible" kegg_type "gene" ] label "aldehyde dehydrogenase 3 family, member A etc.
(Aldh3a1, AHDC, Ahd-c, Aldh, Aldh3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 645 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5440.05 y 2040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29531" kegg_name "rno:29531" kegg_reaction0 "rn:R01372" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "4-hydroxyphenylpyruvate dioxygenase
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"no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00596" kegg_name "cpd:C00596" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 648 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2800.05 y 4480.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00180" kegg_name "cpd:C00180" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 649 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5120.05 y 2320.05 w 5.0 h 5.0 fill 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5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16666" kegg_name "cpd:C16666" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 657 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 460.05 y 2100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00323" kegg_name "cpd:C00323" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 658 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ 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"http://www.kegg.jp/dbget-bin/www_bget?C01575" kegg_name "cpd:C01575" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 664 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3080.05 y 4800.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02765" kegg_name "cpd:C02765" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 665 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3080.05 y 4920.05 w 5.0 h 5.0 fill "#FFFFFF" outline 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kegg_reaction0 "rn:R02287" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "formiminotransferase cyclodeaminase
(Ftcd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 671 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7360.05 y 1500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288259" kegg_name "rno:288259" kegg_reaction0 "rn:R04326" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphoribosylglycinamide formyltransferase
(Gart)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 672 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7530.05 y 1670.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:89833" kegg_name "rno:89833" kegg_reaction0 "rn:R02302" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "formiminotransferase cyclodeaminase
(Ftcd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 673 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7250.0 y 1690.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:89833" kegg_name "rno:89833" kegg_reaction0 "rn:R03189" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "formiminotransferase cyclodeaminase
(Ftcd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 674 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 7440.0 y 1550.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:305248+rno:313410+rno:64300+rno:680308" kegg_name "rno:305248 rno:313410 rno:64300 rno:680308" kegg_reaction0 "rn:R01655" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like etc.
(Mthfd2l, RGD1310879 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 675 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7360.05 y 1690.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03479" kegg_name "cpd:C03479" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 676 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7620.05 y 1730.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00440" kegg_name "cpd:C00440" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 677 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7530.05 y 1730.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00664" kegg_name "cpd:C00664" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 678 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7410.0 y 1620.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:300886" kegg_name "rno:300886" kegg_reaction0 "rn:R02301" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
(Mthfs)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 679 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7470.0 y 1650.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:306586" kegg_name "rno:306586" kegg_reaction0 "rn:R02300" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aminomethyltransferase
(Amt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 680 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7290.0 y 1640.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:315763" kegg_name "rno:315763" kegg_reaction0 "rn:R03940" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial methionyl-tRNA formyltransferase
(Mtfmt, RGD1309462)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 681 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7290.0 y 1610.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:299699+rno:64392" kegg_name "rno:299699 rno:64392" kegg_reaction0 "rn:R00941" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde dehydrogenase 1 family, member L etc.
(Aldh1l2, RGD1309458 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 682 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 7290.0 y 1530.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:361472+rno:64300" kegg_name "rno:361472 rno:64300" kegg_reaction0 "rn:R00943" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like etc.
(Mthfd1l, Fthfsdc1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 683 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7290.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288259" kegg_name "rno:288259" kegg_reaction0 "rn:R04325" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "phosphoribosylglycinamide formyltransferase
(Gart)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 684 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7290.0 y 1670.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81643" kegg_name "rno:81643" kegg_reaction0 "rn:R04560" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
(Atic)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 685 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 7420.05 y 1460.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81522" kegg_name "rno:81522" kegg_reaction0 "rn:R00946" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "5-methyltetrahydrofolate-homocysteine methyltransferase
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kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06032" kegg_name "cpd:C06032" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 688 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 2700.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02226" kegg_name "cpd:C02226" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 689 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5060.05 y 2700.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02612" kegg_name "cpd:C02612" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 690 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5860.05 y 3080.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C06006" kegg_name "cpd:C06006" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor 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(Chka, CK-R, Chk etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 729 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1800.05 y 1500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:89841" kegg_name "rno:89841" kegg_reaction0 "rn:R02038" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphate cytidylyltransferase 2, ethanolamine
(Pcyt2, ET)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 730 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 1660.0 y 1560.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29194+rno:29367+rno:312828+rno:360843" kegg_name "rno:29194 rno:29367 rno:312828 rno:360843" kegg_reaction0 "rn:R01468" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "choline kinase alpha etc.
(Chka, CK-R, Chk etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 731 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2440.0 y 1380.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25096+rno:25097" kegg_name "rno:25096 rno:25097" kegg_reaction0 "rn:R01310" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase D etc.
(Pld1, Pld1a, Pld1b, Plda, Pldb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 732 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2310.0 y 1570.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25096+rno:25097" kegg_name "rno:25096 rno:25097" kegg_reaction0 "rn:R02051" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase D etc.
(Pld1, Pld1a, Pld1b, Plda, Pldb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 733 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2460.05 y 1580.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192260" kegg_name "rno:192260" kegg_reaction0 "rn:R01802" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "CDP-diacylglycerol--inositol 3-phosphatidyltransferase
(Cdipt, Pis, Pis1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 734 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1660.0 y 1480.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287644" kegg_name "rno:287644" kegg_reaction0 "rn:R06870" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatase, orphan 1
(Phospho1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 735 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 1360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:363159+rno:60666" kegg_name "rno:363159 rno:60666" kegg_reaction0 "rn:R00842" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glycerol-3-phosphate dehydrogenase 1-like etc.
(Gpd1l, RGD1560123 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 736 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.0 y 1330.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25062" kegg_name "rno:25062" kegg_reaction0 "rn:R00848" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glycerol-3-phosphate dehydrogenase 2, mitochondrial
(Gpd2, mtGPDH)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 737 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1960.0 y 1520.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:310773+rno:362713" kegg_name "rno:310773 rno:362713" kegg_reaction0 "rn:R02057" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "choline/ethanolamine phosphotransferase etc.
(Cept1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 738 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2400.05 y 1540.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114101+rno:81925" kegg_name "rno:114101 rno:81925" kegg_reaction0 "rn:R01799" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase etc.
(Cds2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 739 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2130.0 y 1560.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:681361" kegg_name "rno:681361" kegg_reaction0 "rn:R02055" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatidylserine decarboxylase
(Pisd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 740 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1660.0 y 1330.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:287644" kegg_name "rno:287644" kegg_reaction0 "rn:R06871" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatase, orphan 1
(Phospho1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 741 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2020.05 y 1540.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25511" kegg_name "rno:25511" kegg_reaction0 "rn:R02056" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatidylethanolamine N-methyltransferase
(Pemt, PHOMETH, Pempt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 742 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2400.05 y 1660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:303698" kegg_name "rno:303698" kegg_reaction0 "rn:R01801" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphatidylglycerophosphate synthase
(Pgs1, RGD1305052)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 743 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2340.05 y 1840.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:366196" kegg_name "rno:366196" kegg_reaction0 "rn:R02030" kegg_reaction1 "rn:R07390" kegg_reaction_type0 "irreversible" kegg_reaction_type1 "irreversible" kegg_type "gene" ] label "cardiolipin synthase
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(Agl)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 776 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3250.05 y 820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288333" kegg_name "rno:288333" kegg_reaction0 "rn:R02110" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glucan (1,4-alpha-), branching enzyme 1
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(Treh)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 778 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3280.05 y 680.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24203+rno:497039" kegg_name "rno:24203 rno:497039" kegg_reaction0 "rn:R02108" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "amylase, alpha 1A (salivary etc.
(Amy1a, Amy1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 779 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3320.05 y 760.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:312272" kegg_name "rno:312272" kegg_reaction0 "rn:R01790" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "maltase-glucoamylase
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(Ganc etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 781 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3310.05 y 820.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24701+rno:25739+rno:64035" kegg_name "rno:24701 rno:25739 rno:64035" kegg_reaction0 "rn:R02111" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phosphorylase, glycogen, muscle etc.
(Pygm, Muscpho etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 782 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3380.0 y 590.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:362029" kegg_name "rno:362029" kegg_reaction0 "rn:R05196" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
(Agl)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 783 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3340.05 y 680.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:497756" kegg_name "rno:497756" kegg_reaction0 "rn:R01791" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "sucrase-isomaltase (alpha-glucosidase)
(Si, SUCIMAL)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 784 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3400.0 y 680.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:312272" kegg_name "rno:312272" kegg_reaction0 "rn:R01791" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "maltase-glucoamylase
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(Lias)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 791 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1450.05 y 3220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:365314" kegg_name "rno:365314" kegg_reaction0 "rn:R07769" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lipoyl(octanoyl) transferase 2 (putative
(Lipt2, RGD1305211)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 792 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1380.05 y 3220.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16239" kegg_name "cpd:C16239" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 793 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1450.05 y 3300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:305348" kegg_name "rno:305348" kegg_reaction0 "rn:R07767" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lipoic acid synthetase
(Lias)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 794 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1260.05 y 3260.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:365314" kegg_name "rno:365314" kegg_reaction0 "rn:R07766" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lipoyl(octanoyl) transferase 2 (putative
(Lipt2, RGD1305211)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 795 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1600.05 y 3220.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316342" kegg_name "rno:316342" kegg_reaction0 "rn:R07771" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lipoyltransferase 1
(Lipt1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 796 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1820.0 y 3300.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00725" kegg_name "cpd:C00725" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 797 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1660.05 y 3220.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16238" kegg_name "cpd:C16238" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 798 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1380.05 y 3300.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16236" kegg_name "cpd:C16236" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 799 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 1520.05 y 3220.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C16237" kegg_name "cpd:C16237" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 800 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2640.0 y 3180.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29411+rno:54398" kegg_name "rno:29411 rno:54398" kegg_reaction0 "rn:R01274" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "palmitoyl-protein thioesterase etc.
(Ppt1, Ppt etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 801 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2870.05 y 2890.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R01278" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 802 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2810.05 y 2470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04737" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 803 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2840.05 y 2340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R03991" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 804 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2730.05 y 2890.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R03989" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 805 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04739" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 806 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 2340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R03858" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 807 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2590.05 y 2890.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R03856" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 808 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2560.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04741" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 809 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2560.05 y 2340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R04742" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 810 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2470.05 y 2890.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R04753" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 811 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2440.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04743" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 812 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2440.05 y 2340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R03778" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 813 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2330.05 y 2890.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R03776" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 814 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2300.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04745" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 815 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2300.05 y 2340.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R04747" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 816 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2190.05 y 2920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29470" kegg_name "rno:29470" kegg_reaction0 "rn:R06985" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "mitochondrial trans-2-enoyl-CoA reductase
(Mecr, Nrbf1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 817 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2130.05 y 2470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170670" kegg_name "rno:170670" kegg_reaction0 "rn:R04748" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
(Hadha, RGD1560655)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 818 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2180.05 y 2360.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:170465+rno:171155" kegg_name "rno:170465 rno:171155" kegg_reaction0 "rn:R01177" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetyl-CoA acyltransferase etc.
(Acaa2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 819 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2660.0 y 3510.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00249+C00162" kegg_name "cpd:C00249 cpd:C00162" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 820 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5270.0 y 2020.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:312952+rno:64473" kegg_name "rno:312952 rno:64473" kegg_reaction0 "rn:R00508" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "inositol monophosphatase domain containing etc.
(Impad1, IMP_3, RGD1306455, gPAPP etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 821 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5130.0 y 2040.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81805" kegg_name "rno:81805" kegg_reaction0 "rn:R00533" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "sulfite oxidase
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(Acadvl, VLCAD)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 934 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2700.05 y 2920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25363" kegg_name "rno:25363" kegg_reaction0 "rn:R03990" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acyl-CoA dehydrogenase, very long chain
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(Ndufab1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 938 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5520.05 y 540.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114630+rno:116455+rno:116550+rno:116664+rno:117596+rno:140608+rno:170667+rno:171082+rno:171374+rno:171375+rno:192241+rno:245958+rno:245965+rno:26196+rno:26197+rno:289407+rno:291969+rno:293650+rno:296981+rno:29754+rno:297566+rno:29757+rno:297797+rno:297932+rno:298103+rno:298451+rno:299159+rno:299971+rno:300677+rno:306478+rno:312488+rno:362802+rno:364460+rno:366545+rno:366614+rno:368044+rno:436582+rno:641434+rno:65262+rno:685232+rno:689271+rno:689961+rno:690441+rno:83615+rno:94170+rno:94271" kegg_name "rno:114630 rno:116455 rno:116550 rno:116664 rno:117596 rno:140608 rno:170667 rno:171082 rno:171374 rno:171375 rno:192241 rno:245958 rno:245965 rno:26196 rno:26197 rno:289407 rno:291969 rno:293650 rno:296981 rno:29754 rno:297566 rno:29757 rno:297797 rno:297932 rno:298103 rno:298451 rno:299159 rno:299971 rno:300677 rno:306478 rno:312488 rno:362802 rno:364460 rno:366545 rno:366614 rno:368044 rno:436582 rno:641434 rno:65262 rno:685232 rno:689271 rno:689961 rno:690441 rno:83615 rno:94170 rno:94271" kegg_type "gene" ] label "ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit etc.
(Atp5g3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 939 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5520.05 y 500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171028+rno:24216+rno:24217" kegg_name "rno:171028 rno:24216 rno:24217" kegg_type "gene" ] label "ATPase, H+/K+ transporting, nongastric, alpha polypeptide etc.
(Atp12a etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 940 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5520.05 y 470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:294504+rno:310856+rno:361663" kegg_name "rno:294504 rno:310856 rno:361663" kegg_type "gene" ] label "pyrophosphatase (inorganic etc.
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graphics [ x 6580.05 y 4100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04188" kegg_name "cpd:C04188" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 957 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6780.05 y 4100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03089" kegg_name "cpd:C03089" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 958 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6780.05 y 3960.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00170" kegg_name "cpd:C00170" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 959 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5710.05 y 3920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24813" kegg_name "rno:24813" kegg_reaction0 "rn:R07396" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "tyrosine aminotransferase
(Tat)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 960 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 4100.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298934" kegg_name "rno:298934" kegg_reaction0 "rn:R07364" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acireductone dioxygenase 1
(Adi1, Alp1, Fe-ARD, MTCBP-1, Ni-ARD)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 961 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5920.05 y 4140.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298934" kegg_name "rno:298934" kegg_reaction0 "rn:R07363" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acireductone dioxygenase 1
(Adi1, Alp1, Fe-ARD, MTCBP-1, Ni-ARD)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 962 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6320.05 y 4100.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:295961" kegg_name "rno:295961" kegg_reaction0 "rn:R07392" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "APAF1 interacting protein
(Apip, RGD1564562)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 963 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6480.0 y 4100.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:288912" kegg_name "rno:288912" kegg_reaction0 "rn:R04420" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
(Mri1, RGD1307789)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 964 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6580.05 y 4020.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:298227" kegg_name "rno:298227" kegg_reaction0 "rn:R01402" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "methylthioadenosine phosphorylase
(Mtap, Cc1-6)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 965 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5740.05 y 3040.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24962" kegg_name "rno:24962" kegg_reaction0 "rn:R01001" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "cystathionase (cystathionine gamma-lyase)
(Cth, H)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 966 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5820.05 y 3400.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24250" kegg_name "rno:24250" kegg_reaction0 "rn:R01290" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "cystathionine beta synthase
(Cbs)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 967 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5710.05 y 3650.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81522" kegg_name "rno:81522" kegg_reaction0 "rn:R00946" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "5-methyltetrahydrofolate-homocysteine methyltransferase
(Mtr, methioninesynthase)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 968 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5770.05 y 3650.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:81508" kegg_name "rno:81508" kegg_reaction0 "rn:R02821" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "betaine-homocysteine S-methyltransferase
(Bhmt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 969 zlevel -1 charting [ background_color "#000000" domainAxis "[unit]" empty_border_width 2.0 empty_border_width_vert 2.0 maxRange 1.0 max_charts_in_column -1 minRange 0.0 rangeAxis "[unit]" rangeStepSize 0.0 show_legend "false" useCustomRange "false" useCustomRangeSteps "false" ] cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 3800.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" component "chart2d_type1" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171347+rno:25331+rno:683630" kegg_name "rno:171347 rno:25331 rno:683630" kegg_reaction0 "rn:R00177" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "methionine adenosyltransferase II, alpha etc.
(Mat2a, Sams2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 970 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 3500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29443+rno:312192+rno:362013" kegg_name "rno:29443 rno:312192 rno:362013" kegg_reaction0 "rn:R00192" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "adenosylhomocysteinase etc.
(Ahcy etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 971 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5920.05 y 3640.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:309680+rno:444984+rno:444985+rno:84350" kegg_name "rno:309680 rno:444984 rno:444985 rno:84350" kegg_reaction0 "rn:R04858" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "A (cytosine-5-)-methyltransferase 3-like etc.
(Dnmt3l etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 972 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5770.05 y 3920.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100360621+rno:298483" kegg_name "rno:100360621 rno:298483" kegg_reaction0 "rn:R00648" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K03334 L-amino-acid oxidase etc.
(DEFINITION rCG53598-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 973 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5920.05 y 3500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00021" kegg_name "cpd:C00021" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 974 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5740.05 y 4100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01180" kegg_name "cpd:C01180" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 975 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.05 y 3500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03539" kegg_name "cpd:C03539" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 976 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6160.05 y 4080.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:305177" kegg_name "rno:305177" kegg_reaction0 "rn:R07395" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "enolase-phosphatase 1
(Enoph1, RGD1309016)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 977 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5420.05 y 1940.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24401+rno:25721" kegg_name "rno:24401 rno:25721" kegg_reaction0 "rn:R02619" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase etc.
(Got1, Aspat, Gaspat etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 978 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5340.05 y 2100.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C05527" kegg_name "cpd:C05527" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 979 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4960.05 y 2300.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24962" kegg_name "rno:24962" kegg_reaction0 "rn:R00782" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "cystathionase (cystathionine gamma-lyase)
(Cth, H)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 980 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5260.0 y 2180.0 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00957" kegg_name "cpd:C00957" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 981 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5400.05 y 2180.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24401+rno:25721" kegg_name "rno:24401 rno:25721" kegg_reaction0 "rn:R00896" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase etc.
(Got1, Aspat, Gaspat etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 982 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6200.0 y 2330.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:66029+rno:681319" kegg_name "rno:66029 rno:681319" kegg_reaction0 "rn:R00678" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "indoleamine 2,3-dioxygenase etc.
(Ido1, Ido, Indo etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 983 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6310.0 y 2400.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100360621+rno:298483" kegg_name "rno:100360621 rno:298483" kegg_reaction0 "rn:R00677" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "RTHOLOGY K03334 L-amino-acid oxidase etc.
(DEFINITION rCG53598-like etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 984 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5980.05 y 2530.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:246281" kegg_name "rno:246281" kegg_reaction0 "rn:R03130" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "acetylserotonin O-methyltransferase
(Asmt)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 985 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5980.0 y 2420.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25120" kegg_name "rno:25120" kegg_reaction0 "rn:R02911" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aralkylamine N-acetyltransferase
(Aanat, AA-NAT, Nat4)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 986 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6060.0 y 2380.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24311" kegg_name "rno:24311" kegg_reaction0 "rn:R02701" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dopa decarboxylase (aromatic L-amino acid decarboxylase)
(Ddc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 987 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5970.0 y 2330.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:688283" kegg_name "rno:688283" kegg_reaction0 "rn:R01959" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "arylformamidase
(Afmid)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 988 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4160.05 y 3130.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:290566+rno:360975" kegg_name "rno:290566 rno:360975" kegg_reaction0 "rn:R01933" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "oxoglutarate dehydrogenase-like (EC:1.2.4.- etc.
(Ogdhl etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 989 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5320.05 y 2660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:171385" kegg_name "rno:171385" kegg_reaction0 "rn:R04323" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aminocarboxymuconate semialdehyde decarboxylase
(Acmsd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 990 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5660.05 y 2660.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:56823" kegg_name "rno:56823" kegg_reaction0 "rn:R02665" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "3-hydroxyanthranilate 3,4-dioxygenase
(Haao)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 991 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 2380.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:59113" kegg_name "rno:59113" kegg_reaction0 "rn:R01960" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
(Kmo)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 992 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 2180.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116682" kegg_name "rno:116682" kegg_reaction0 "rn:R00987" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "kynureninase
(Kynu)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 993 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5840.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:116682" kegg_name "rno:116682" kegg_reaction0 "rn:R02668" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "kynureninase
(Kynu)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 994 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6200.0 y 2300.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:64206" kegg_name "rno:64206" kegg_reaction0 "rn:R00678" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "tryptophan 2,3-dioxygenase
(Tdo2, TO, Tdo)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 995 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6200.0 y 2380.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24848+rno:317675" kegg_name "rno:24848 rno:317675" kegg_reaction0 "rn:R01814" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "tryptophan hydroxylase etc.
(Tph1, Tph etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 996 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5880.05 y 2260.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29416+rno:311844+rno:541589" kegg_name "rno:29416 rno:311844 rno:541589" kegg_reaction0 "rn:R01956" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aminoadipate aminotransferase etc.
(Aadat, Kat2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 997 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6370.0 y 2330.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24311" kegg_name "rno:24311" kegg_reaction0 "rn:R00685" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dopa decarboxylase (aromatic L-amino acid decarboxylase)
(Ddc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 998 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5900.0 y 2420.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25750+rno:29253" kegg_name "rno:25750 rno:29253" kegg_reaction0 "rn:R02908" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "monoamine oxidase B etc.
(Maob etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 999 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6220.05 y 2620.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291450+rno:29539+rno:29651+rno:298079+rno:64040+rno:65183" kegg_name "rno:291450 rno:29539 rno:29651 rno:298079 rno:64040 rno:65183" kegg_reaction0 "rn:R02678" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde dehydrogenase 7 family, member A etc.
(Aldh7a1, antiquitin etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1000 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5870.05 y 2530.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291450+rno:29539+rno:29651+rno:298079+rno:64040+rno:65183" kegg_name "rno:291450 rno:29539 rno:29651 rno:298079 rno:64040 rno:65183" kegg_reaction0 "rn:R04903" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde dehydrogenase 7 family, member A etc.
(Aldh7a1, antiquitin etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1001 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5930.05 y 2530.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316421+rno:316424+rno:493909+rno:54349" kegg_name "rno:316421 rno:316424 rno:493909 rno:54349" kegg_reaction0 "rn:R04904" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "aldehyde oxidase 3-like etc.
(Aox3l1, Aox2 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1002 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6420.05 y 2470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:25750+rno:29253" kegg_name "rno:25750 rno:29253" kegg_reaction0 "rn:R02173" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "monoamine oxidase B etc.
(Maob etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1003 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6480.05 y 2470.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:65029" kegg_name "rno:65029" kegg_reaction0 "rn:R02173" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "amiloride binding protein 1 (amine oxidase, copper-containing)
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(Cept1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1042 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2140.05 y 2020.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:310773+rno:362866" kegg_name "rno:310773 rno:362866" kegg_reaction0 "rn:R07389" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "choline/ethanolamine phosphotransferase etc.
(Cept1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1043 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2530.0 y 2160.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:114113+rno:301265+rno:313611+rno:64189+rno:83572" kegg_name "rno:114113 rno:301265 rno:313611 rno:64189 rno:83572" kegg_reaction0 "rn:R04452" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "platelet-activating factor acetylhydrolase 1b, catalytic subunit etc.
(Pafah1b3 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1044 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2630.0 y 2160.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192259+rno:24653+rno:289733+rno:29354+rno:29359+rno:29387+rno:29526+rno:296091+rno:29692+rno:298579+rno:311341+rno:360426+rno:362039+rno:367415+rno:690388+rno:691813+rno:691905+rno:691907" kegg_name "rno:192259 rno:24653 rno:289733 rno:29354 rno:29359 rno:29387 rno:29526 rno:296091 rno:29692 rno:298579 rno:311341 rno:360426 rno:362039 rno:367415 rno:690388 rno:691813 rno:691905 rno:691907" kegg_reaction0 "rn:R07387" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase B etc.
(Plb1, Phlpb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1045 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2630.0 y 2200.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100359680+rno:361467" kegg_name "rno:100359680 rno:361467" kegg_reaction0 "rn:R03438" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lysophosphatidylcholine acyltransferase etc.
(Lpcat2, LPCAT-2, RGD1563994 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1046 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2530.0 y 2200.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:100359680+rno:296048+rno:361467" kegg_name "rno:100359680 rno:296048 rno:361467" kegg_reaction0 "rn:R03437" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lysophosphatidylcholine acyltransferase etc.
(Lpcat2, LPCAT-2, RGD1563994 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1047 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2180.0 y 2170.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:192259+rno:24653+rno:289733+rno:29354+rno:29359+rno:29387+rno:29526+rno:296091+rno:29692+rno:298579+rno:311341+rno:360426+rno:362039+rno:367415+rno:690388+rno:691813+rno:691905+rno:691907" kegg_name "rno:192259 rno:24653 rno:289733 rno:29354 rno:29359 rno:29387 rno:29526 rno:296091 rno:29692 rno:298579 rno:311341 rno:360426 rno:362039 rno:367415 rno:690388 rno:691813 rno:691905 rno:691907" kegg_reaction0 "rn:R07379" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "phospholipase B etc.
(Plb1, Phlpb etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1048 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2180.0 y 2210.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:296048" kegg_name "rno:296048" kegg_reaction0 "rn:R04413" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "lysophosphatidylcholine acyltransferase 4
(Lpcat4, Agpat7, RGD1311177)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1049 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 2280.05 y 2190.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:310773+rno:362713" kegg_name "rno:310773 rno:362713" kegg_reaction0 "rn:R07384" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "choline/ethanolamine phosphotransferase etc.
(Cept1 etc.)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1050 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5620.05 y 2700.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:89833" kegg_name "rno:89833" kegg_reaction0 "rn:R02287" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "formiminotransferase cyclodeaminase
(Ftcd)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1051 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5620.05 y 2560.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:299735" kegg_name "rno:299735" kegg_reaction0 "rn:R02288" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "amidohydrolase domain containing 1
(Amdhd1, RGD1308879)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1052 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5580.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:685999" kegg_name "rno:685999" kegg_reaction0 "rn:R02914" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "urocanase domain containing
(Uroc1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1053 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5260.05 y 2500.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:29301" kegg_name "rno:29301" kegg_reaction0 "rn:R01168" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "histidine ammonia lyase
(Hal, histidase)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1054 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6130.05 y 1380.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:291394" kegg_name "rno:291394" kegg_reaction0 "rn:R01166" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "CNDP dipeptidase 2 (metallopeptidase M20 family)
(Cndp2)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1055 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5090.05 y 2440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24311" kegg_name "rno:24311" kegg_reaction0 "rn:R01167" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "dopa decarboxylase (aromatic L-amino acid decarboxylase)
(Ddc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1056 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5030.05 y 2440.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:24443" kegg_name "rno:24443" kegg_reaction0 "rn:R01167" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "histidine decarboxylase
(Hdc)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1057 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 6070.05 y 1380.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:307212" kegg_name "rno:307212" kegg_reaction0 "rn:R01166" kegg_reaction_type0 "irreversible" kegg_type "gene" ] label "carnosine dipeptidase 1 (metallopeptidase M20 family)
(Cndp1)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1058 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 1640.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02739" kegg_name "cpd:C02739" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1059 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 1780.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C02741" kegg_name "cpd:C02741" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1060 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 1920.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04896" kegg_name "cpd:C04896" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1061 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 2060.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04916" kegg_name "cpd:C04916" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1062 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 2200.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C04666" kegg_name "cpd:C04666" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1063 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 2380.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01267" kegg_name "cpd:C01267" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1064 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4620.05 y 2500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01100" kegg_name "cpd:C01100" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1065 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4800.05 y 2500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00860" kegg_name "cpd:C00860" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1066 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5060.05 y 2380.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00388" kegg_name "cpd:C00388" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1067 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4900.05 y 2500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C01929" kegg_name "cpd:C01929" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1068 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5480.05 y 2500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00785" kegg_name "cpd:C00785" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1069 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5620.05 y 2500.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C03680" kegg_name "cpd:C03680" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1070 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 5620.05 y 2600.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00439" kegg_name "cpd:C00439" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1071 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 3070.05 y 3560.05 w 5.0 h 5.0 fill "#FFFFFF" outline "#333333" depth_ 5.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "circle" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?C00085" kegg_name "cpd:C00085" kegg_type "compound" ] label "" labelgraphics [ alignment "center" anchor "auto_outside" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1072 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4220.05 y 1260.05 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:501157" kegg_name "rno:501157" kegg_reaction0 "rn:R01529" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "ribulose-5-phosphate-3-epimerase
(Rpe)" labelgraphics [ alignment "center" anchor "c" color "#000000" fontName "Arial" fontSize 10 fontStyle "plain" type "text" ] model [ drawLabels "true" ignoreNodeOutlineColor "false" transLevel 0.0 ] ] node [ id 1073 zlevel -1 cluster [ cluster "Enzymes_Layer" ] graphics [ x 4100.0 y 1200.0 w 46.0 h 18.0 fill "#CCFFCC" outline "#000000" depth_ 18.0 frameThickness 1.0 gradient 0.0 rounding 5.0 type "observable" z_ 0.0 ] kegg [ grouppart "no" kegg_link "http://www.kegg.jp/dbget-bin/www_bget?rno:316067" kegg_name "rno:316067" kegg_reaction0 "rn:R01639" kegg_reaction_type0 "reversible" kegg_type "gene" ] label "xylulokinase homolog (H. influenzae)
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